Alt üriner sistem işlev bozukluğu bulunan çocuklarda ürodinami ve ultrasonografi bulgularının karşılaştırılması
Amaç: Bu çalışmanın amacı, çocuklarda ultrason aracılığı ile mesane duvar kalınlığı ölçümünün alt üriner sistem işlev bozukluğu tanısındaki rolünü belirlemektir. Gereç ve yöntem: Çalışmamızda Cerrahpaşa Tıp Fakültesi’nde 2007-2009 yılları arasında alt üriner sistem işlev bozukluğu nedeniyle takip ve tedavi edilen ve ürodinamik incelemesi yapılmış olan 114 çocuk hasta geriye dönük olarak değerlendirildi. Hastalar stabil olmayan detrusor kasılması varlığı ve mesane duvar kalınlıklarına göre sınıflandırıldı. Hastaların ebeveynlerinden aydınlatılmış onam formu alındı. Bulgular: Çalışma grubumuzun 13’ünde anatomik, 40’ında nörolojik neden saptanırken, 61 hasta idiyopatik grubu oluşturdu. Ürodinamik incelemede 66 hastada stabil olmayan detrusor kasılması gözlenirken, 48 hastada kasılma saptanmadı. Ultrasonografide stabil olmayan detrusor kasılması saptanan hastaların 22’sinde (22/66) mesane duvarı kalınlığı ince bulundu. 44 hastada ise (44/66) mesane duvarları kalın bulundu. Çıkarımlar: Çalışmamız sonucunda sadece sonografik mesane duvar kalınlığı ölçümünün alt üriner sistem işlev bozukluğu tanısı koymada yetersiz kalacağı ve ürodinamik çalışmaların yerini alamayacağını düşünmekteyiz. Alt üriner sistem işlev bozukluğu olan hastaların değerlendirilmesinde, tedavi planının belirlenmesinde ve hasta izleminde sonografi ve ürodinaminin birbirlerine seçenek değil, birbirini tamamlayıcı yöntemler olduğu sonucuna varıldı. (Türk Ped Arfl 2011; 46: 241-5)
Comparison of urodynamic studies and sonographic findings in children with lower urinary system dysfunction
Purpose: The purpose of this study is to determine the role of sonographic bladder wall thickness measurement in children with lower urinary system dysfunction. Material and methods: In this study, we reviewed 114 pediatric patients who underwent urodynamic studies for lower urinary system dysfunction between 2007-2009 at Istanbul University Cerrahpasa Medical Faculty. The patients were classified according to instable detrusor contractions and bladder wall thicknesses. Informed consent form was obtained from their parents. Results: Our study groups consisted with anatomical reasons (n=13), neurological problems (n=40) and idiopathic group (n=61). Urodynamic study detected unstable detrusor contractions in 66 patients while it did not determine contraction in 48 patients. Ultrasonography in 22 patients with unstable detrusor contraction (22/66) of bladder wall thickness was thin. In 44 patients (44/66) bladder wall thickness was detected thick. Conclusions: Our study suggests that the measurement of bladder wall thickness alone can not diagnose lower urinary system dysfunction correctly and can not replace urodynamic studies. Sonography and urodynamic studies are complementary rather than alternative modalities in evaluation and management of children with lower urinary system dysfunction. (Turk Arch Ped 2011; 46: 241-5)
___
- 1. Koff SA, Jayanthi VR Section B. Non-neurogenic lower urinary tract dysfunction. In: Walsh PC, Retik AB, Vaughan ED, Wein AJ, (eds) Campbell’s urology. 8th ed. Philadelphia: Saunders, 2002: 2261-83.
- 2. Fotter R, Riccabona M. Funktionelle störungen des unteren harntrakts im kindesalter. Radiologe 2005; 45: 1085-91.
- 3. Bauer SB. Section A. Neuropathic dysfunction of the lower urinary tract. In: Walsh PC, Retik AB, Vaughan ED, Wein AJ, (eds) Campbell’s urology. 8th ed. Philadelphia: Saunders, 2002: 2231-61.
- 4. Allen TD. Forty years experience with voiding dysfunction. BJU Int 2003; 92: 15-22.
- 5. Naseer S, Steinhardt GF. New renal scars in children with urinary tract infections, vesicoureteral reflux and voiding dysfunction: a prospective evaluation. J Urol 1997; 158: 566-8.
- 6. Snodgrass W. Relationship of voiding dysfunction to urinary tract infection and vesicoureteral reflux in children. Urology 1991; 38: 341-4.
- 7. Allen TD. Commentary: voiding dysfunction and reflux. J Urol 1992; 148: 1706-7.
- 8. McKenna PH, Herndon CDA. Voiding dysfunction associated with incontinence, vesicoureteral reflux and recurrent urinary tract infections. Curr Opin Urol 2000; 10: 599-606.
- 9. Silva JM, Santos Diniz JS, Marino VS, et al. Clinical course of 735 children and adolescents with primary vesicoureteral reflux. Pediatr Nephrol 2006; 21: 981-8.
- 10. Homayoon K, Chen JJ, Cummings JM, et al. Voiding dysfunction: outcome in infants with congenital vesicoureteral reflux. Urology 2005; 66: 1091-4.
- 11. Leonardo CR, Filgueiras MFT, Vasconcelos MM, Roberta Vasconcelos R, Marino VP. Risk factors for renal scarring in children and adolescents with lower urinary tract dysfunction. Pediatr Nephrol 2007; 22: 1891-6.
- 12. Soygur T, Arikan N, Yesilli C, et al. Relationship among pediatric voiding dysfunction and vesicoureteral reflux and renal scars. Urology 1999; 54: 905-8.
- 13. Herndon CDA, McKenna PH. The treatment of dysfunctional elimination decreases urinary tract infections and surgery in children with vesicoureteral reflux. Am Acad of Pediatr Annual Meeting 2000; 185.
- 14. Yeung CK, Sreedhar B, Leung YF, et al. Correlation between ultrasonographic bladder measurements and urodynamic findings in children with recurrent urinary tract infection. BJU Int 2007; 99: 651-5.
- 15. Levin RM, Monson FC, Haugaard N, et al. Genetic and cellular characteristics of bladder outlet obstruction. Urol Clin North Am 1995; 22: 263-83.
- 16. Bagli DJ, Van Savage JG, Khoury AE, et al. Basic fibroblast growth factor in the urine of children with voiding pathology. J Urol 1997; 158: 1123-7.
- 17. Jequier S, Rousseau O. Sonographic measurements of the normal bladder wall in children. Am J Roentgenol 1987; 149: 563-6.
- 18. Uluocak N, Erdemir F, Parlaktas BS, et al. Bladder wall thickness in healthy school-aged children. Urology 2007; 69: 763-6.
- 19. Müller L, Bergström T, Hellström, et al. Standardised ultrasound method for assessing detrusor muscle thickness in children. J Urol 2000; 164: 134-8.
- 20. Cvitkovic-Kuzmic A, Brkljacic B, Ivankovic D, et al. Ultrasound assessment of detrusor muscle thickness in children with non-neuropathic bladder/sphincter dysfunction. Eur Urol 2002; 41: 214-8.
- 21. Kumar R, Singhal N, Gupta M, et al. Evaluation of clinico urodynamic outcome of bladder dysfunction after surgery in children with spinal dysraphism-a prospective study. Acta Neurochir 2008; 150: 129-37.
- 22. Silva JA, Gonsalves Mde C, Saverio AP, et al. Lower urinary tract dysfunction and ultrasound assessment of bladder wall thickness in children with cerebral palsy. Urology 2010; 76: 943-5.
- 23. Tanaka H, Matsuda M, Moriya K, et al. Ultrasonographic measurement of bladder wall thickness as a risk factor for upper urinary tract deterioration in children with myelodysplasia. J Urol 2008; 180: 312-6.
- 24. Glassberg KI, Combs AJ, Horowitz M. Nonneurogenic voiding disorders in children and adolescents: clinical and videourodynamic findings in 4 specific conditions. J Urol 2010; 184: 2123-7.