Taste Alteration in Cancer Patients Receiving Chemotherapy: A Cross-Sectional Study

Taste Alteration in Cancer Patients Receiving Chemotherapy: A Cross-Sectional Study

OBJECTIVEThis study aimed to investigate nutrition in cancer patients, chemotherapy-induced taste alterations andthe factors affecting these taste alterations.METHODSThis study was planned as a cross-sectional study. Patients who had received chemotherapy at least onceand had been on chemotherapy for the last 7-10 days (n=112) were included in this study. The data werecollected using the Patient-Generated Subjective Global Assessment, the National Cancer Institute’sCommon Terminology Criteria for Adverse Events and the Chemotherapy-induced Taste AlterationScale (CiTAS).RESULTSThe CiTAS score was higher in female cancer patients. Patients with nausea 2.19 (SD=1.00) and vomiting 3.13 (SD=1.21) had higher scores on the taste disorder subscale of the CiTAS, while patients withvomiting 3.00 (SD=1.42) had higher scores on the general taste alterations subscale (p

___

  • 1. Okada N, Hanafusa T, Abe S, Sato C, Nakamura T, Teraoka K, et al. Evaluation of the risk factors associated with high-dose chemotherapy-induced dysgeusia in patients undergoing autologous hematopoietic stem cell transplantation: possible usefulness of cryotherapy in dysgeusia prevention. Support Care Cancer 2016;24(9):3979–85.
  • 2. Bernhardson BM, Tishelman C, Rutqvist LE. Self-reported taste and smell changes during cancer chemotherapy. Support Care Cancer 2008;16,275–83.
  • 3. Speck RM, DeMichele A, Farrar JT, Hennessy S, Mao JJ, Stineman MG, et al. Taste alteration in breast cancer patients treated with taxane chemotherapy: experience, effect, and coping strategies. Support Care Cancer 2013;21:549–55.
  • 4. Gamper EM, Zabernigg A, Wintner, LM, Giesinger J M., Oberguggenberger A, Kemmler G, et al. Coming to your senses: detecting taste and smell alterations in chemotherapy patients. A systematic review. J Pain Symptom Manage 2012;44(6):880–95.
  • 5. Spotten L, Corish C, Lorton C, Dhuibhir PU, O’Donoghue N, O’Connor B, et al. Subjective taste and smell changes in treatment-naive people with solid tumours. Support Care Cancer 2016; 24:3201–08.
  • 6. Hutton JL, Baracos VE, Wismer WV. Chemosensory dysfunction is a primary factor in the evolution of declining nutritional status and quality of life in patients with advanced cancer. J Pain Symptom Manage 2007;33:156–65.
  • 7. Brisbois TD, de Kock IH, Watanabe SM., Baracos VE, Wismer WV. Characterization of chemosensory alterations in advanced cancer reveals specific chemosensory phenotypes impacting dietary intake and quality of life. J Pain Symptom Manage. 2011;41:673–83.
  • 8. Grant M, Kravits K. Symptoms and their impact on nutrition. In Semin Oncol Nurs 2000;16:113–21.
  • 9. Ravasco P. Aspects of taste and compliance in patients with cancer. Eur J Oncol Nur 2005;9:84–91.
  • 10.Sánchez-Lara K, Sosa-Sánchez R, Green-Renner D, Rodríguez C, Laviano A, Motola-Kuba D, et al. Influence of taste disorders on dietary behaviors in cancer patients under chemotherapy. Nutr J 2010;24:9–15.
  • 11.Coa KI, Epstein JB, Ettinger D, Jatoi A, McManus K, Platek ME, et al. The impact of cancer treatment on the diets and food preferences of patients receiving outpatient treatment. Nutr Cancer 2015;67:339–53.
  • 12.Ponticelli E, Clari M, Frigerio S, De Clemente A, Bergese I, Scavino E, et al. Dysgeusia and health‐related quality of life of cancer patients receiving chemotherapy: A cross‐sectional study. Eur J Cancer Care 2017;26(2)1–7.
  • 12.McGreevy J, Orrevall Y, Belqaid K, Wismer W, Tishelman C, Bernhardson. Characteristics of taste and smell alterations reported by patients after starting treatment for lung cancer. Support Care Cancer 2014;22:2635–44.
  • 13.Ottery FD. Definition of standardized nutritional assessment and interventional pathways in oncology. Nutrition 1996;12:15–9.
  • 14.Bauer J, Capra S, Ferguson M. Use of the scored Patient-Generated Subjective Global Assessment (PGSGA) as a nutrition assessment tool in patients with cancer. Eur J Clin Nutr 2002;56:779–85.
  • 15.https://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03/ CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf
  • 16.Kano T, Kanda K. Development and validation of a chemotherapy-induced taste alteration scale. Oncol Nurs Forum 2013;40,79–85.
  • 17.Sozeri E, Kutlutürkan S. The validity and reliability of Turkish version of the chemotherapy-induced taste alteration scale (CiTAS). Clin Nurs Res 2018;27(2):235–49.
  • 18.Epstein JB, Phillips N, Parry J, Epstein MS, Nevill T, Stevenson-Moore P. Quality of life, taste, olfactory and oral function following high-dose chemotherapy and allogeneic hematopoietic cell transplantation. Bone Marrow Transplant 2002;30:785–92.
  • 19.Zabernigg A, Gamper EM, Giesinger J M, Rumpold G, Kemmler G, Gattringer K, et al. Taste alterations in cancer patients receiving chemotherapy: a neglected side effect?. Oncologist 2010;15:913–20.
  • 20.IJpma I, Timmermans ER, Renken RJ, Ter Horst GJ, Reyners AK. Metallic taste in cancer patients treated with systemic therapy: A questionnaire-based study. Nutr Cancer 2017;69:140–5.
  • 21.Strasser F, Demmer R, Böhme C, Schmitz SF, Thuerlimann B, Cerny T, et al. Prevention of docetaxel- or paclitaxel associated taste alterations in cancer patients with oral glutamine: a randomized, placebo-controlled, double-blind study. Oncologist 2008;13(3):337–46.
  • 22.Sözeri E, Kutlutürkan S.Taste Alteration in Patients Receiving Chemotherapy. J Breast Health 2015;11:81–7.
  • 23.Farrell C, Brearley SG, Pilling M, Molassiotis A. The impact of chemotherapy-related nausea on patients’ nutritional status, psychological distress and quality of life. Support Care Cancer 2013;21:59–66.
  • 24.Yamagishi A, Morita T, Miyashita M, Kimura F. Symptom prevalence and longitudinal follow-up in cancer outpatients receiving chemotherapy. J Pain Symptom Manage 2009;37:823–30.
  • 25.Boussios S, Pentheroudakis G, Katsanos K, Pavlidis N. Systemic treatment-induced gastrointestinal toxicity: incidence, clinical presentation and management. Ann Gastroenterol 2012;25:106–18.
  • 26.Hovan AJ, Williams PM, Stevenson-Moore P, Wahlin YB, OhrnK E, Elting LS, et a.l A systematic review of dysgeusia induced by cancer therapies. Support Care Cancer 2010;18:1081–7.
  • 27.Turcott JG, Juárez-Hernández E, De la Torre-Vallejo M, Sánchez-Lara K, Luvian-Morales J, Arrieta O. Value: Changes in the Detection and Recognition Thresholds of Three Basic Tastes in Lung Cancer Patients Receiving Cisplatin and Paclitaxel and Its Association with Nutritional and Quality of Life Parameters. Nutr Cancer 2016;68(2):241–9.
  • 28.Bernhardson BM, Tishelman C, Rutqvist LE. Taste and smell changes in patients receiving cancer chemotherapy: distress, impact on daily life, and self-care strategies. Cancer Nurs 2009;32:45–54.
Türk Onkoloji Dergisi-Cover
  • ISSN: 1300-7467
  • Başlangıç: 2015
  • Yayıncı: Ali Cangül
Sayıdaki Diğer Makaleler

Validity and Reliability of Turkish Version the Family Inventory of Needs-Pediatric II: An Inventory to Identify Care Needs of Parents of Children with Cancer

Ayşe AY, Leanne MONTEROSSO, HANDAN BOZTEPE

Comparison of Anisotropic Analytical Algorithm and Acuros XB Calculation Algorithms on Intensity-modulated Radiotherapy and Volumetric Modulated Arc Therapy Techniques for Nasal Cavity and Paranasal Sinus Tumors: Effects on Integral Radiation Dose

Züleyha AKGÜN, Aydın ÇAKIR

Mutational Screening of miR-17-92 Cluster and miR-34a by DNA Sequencing in Childhood High-Grade Brain Tumors

Aylar POYRAZ, Avni SARAÇ, Kemali BAYKANER, Ferda ALPASLAN PINARLI, İrem DOĞAN, Aynur OĞUZ, Ceyda KARADENİZ, Abdullah EKMEKÇİ, Arzu OKUR, Faruk GÜÇLÜ PINARLI

Geriatric Assessment in Oncology: G8 Screening Tool Validation and Reliability Study

İmatullah AKYAR, Deniz KOÇOĞLU TANYER, Esra ATAKUL

A case of Pulmonary Inflammatory Fibroblastic Tumor with Clinical, Radiological, Histopathological Features and 2-year follow-up Results and Review of the Literature

Ömer ÖZBUDAK, Hülya DİROL

The Effects of the Amount of Bladder Filling on Normal Tissue Doses in 3-dimensional HDR Vaginal Cuff Brachy Therapy

Şeyda KINAY, Recep KANDEMİR, İlhami ER, Ayşe Nur DEMİRAL, Funda OBUZ

Stereotactic Body Radiotherapy for Adrenal Gland Metastases: Single-Center Experience

Gökhan YAPRAK, Cengiz GEMİCİ, Harun DEMİR, Naciye IŞIK, Melike PEKYÜREK

Taste Alteration in Cancer Patients Receiving Chemotherapy: A Cross-Sectional Study

Mevlüde ERGEN, Fatma ARIKAN, Sevinç KUTLUTÜRKAN, Elif Sözeri ÖZTÜRK

Factors that are Effective in Surgery Preferences of Patients Diagnosed with Breast Cancer who are Admitted to Radiation Oncology Clinics

Sema YILMAZ RAKICI

Breast Care Nursing in the World and Turkey

Derya ÇINAR, Ayfer KARADAKOVAN