Mehmet Salih GÜREL, Esma İNAN YÜKSEL, Remzi ABALI, Aslı VEFA ERDEMİR, Erol BOZKURT

VULVAR EKSTRAMAMMARİAN PAGET HASTALIĞI

Ekstramammarian Paget hastalığı (EMPH) başlıca anogenital bölge olmak üzere apokrin bezlerin yoğun olduğu bölgelerde ortaya çıkan, nadir görülen bir intraepitelyal karsinomdur. Primer veya altta yatan malignitelere sekonder olarak ortaya çıkabilir. Genellikle keskin sınırlı ekzematize veya erode plak şeklinde ortaya çıkar ve birçok farklı dermatozu taklit edebilir. Bu nedenle EMPH kronik vulvar dermatozların ayırıcı tanıda daima hatırlanmalıdır. Bu yayında internal malignitenin eşlik etmediği, ilki hipopigmente plak, diğeri vejetatif kitle şeklinde, iki EMPD olgusu sunulmuştur.

Anahtar Kelimeler:

Ekstramammarian Paget hastalığı, vulva

EXTRAMAMMARY PAGET’S DİSEASE OF THE VULVA

Extramammary Paget’s disease (EMPD) is a rare intraepithelial carcinoma, that presents on apocrine-bearing skin areas, mainly on anogenital region. EMPD may occur primary or secondary to an underlying malignancy. It usually manifests as well-demarcated, eczematous or eroded plaques and can mimic many different dermatosis. Therefore, EMPD always be considered in the differantial diagnosis of cronic vulvar dermatoses. In this report, two EMPD cases without association with internal malignancy are reported ;one with a hypopigmentated plaque and the other with vegetative appearence.

Keywords:

Extramammary Paget’s disease, vulva,

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