UTERİN SERVİKSİN MEZONEFRİK ADENOKARSİNOMU:OLGU SUNUMU

Mezonefrik karsinom mezonefrik (Wolf) kanalların kalıntılarından köken almakta olup servikal epitelial tümörlerin nadir bir alt tipidir. Literatürde az sayıda hasta olduğundan; tedavi, prognoz ve sonuçlar hala net değildir. Bu makalede; 52 yaşında, servikal kanser nedeniyle tip III radikal histerektomi, bilateral salpingoooferektomi ve bilateral pelvik lenf nodu disseksiyonu uygulanmış hasta sunuldu. Patoloji sonucu servikal mesonefrik adenokarsinom olarak rapor edilen hastada lenf nodu tutulumu, parametrial tutulum ve cerrahi sınırlarda tumor yoktur. Adjuvan tedavi uygulanmamıştır. Hasta 2 yıldır hastalıksız ve rekürrenssiz takip edimektedir.

MESONEPHRIC ADENOCARCINOMA OF THE UTERINE CERVIX: A CASE REPORT

Mesonephric carcinomas, which derive from the remnants of the paired mesonephric (Wolfian) ducts, are a rare subtype of epithelial tumors of the uterine cervix. Because of the few cases reported in literature; the therapy, prognosis and outcome are still not clear. 52 years old women underwent a type III radical hysterectomy, bilateral salpingo-oophorectomy and bilateral pelvic lymph node dissection because of the cervical cancer was presented in our report. Mesonephric adenocarcinoma with no lymph node metastasis, no parametrial tumoral spread and free surgical margins were reported in certain pathology. She did not receive adjuvant therapy. She has been followed-up for 2 years without recurrence

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  • 3. Dierickx A, Göker M, Braems G, Tummers P, Van den Broecke R. Mesonephric adenocarcinoma of the cervix: Case report and literature review. Gynecol Oncol Rep, 2016; 17: 7-11.
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  • 5. Kenny SL, McBride HA, Jamison J, McCluggage WG. Mesonephric adenocarcinomas of the uterine cervix and corpus: HPV-negative neoplasms that are commonly PAX8, CA125, and HMGA2 positive and that may be immunoreactive with TTF1 and hepatocyte nuclear factor 1-beta. Am J Surg Pathol, 2012; 36(6): 799-807.
  • 6. Park KJ, Kiyokawa T, Soslow RA, Lamb CA, Oliva E, Zivanovic O, Juretzka MM, Pirog EC. Unusual endocervical adenocarcinomas: an immunohistochemical analysis with molecular detection of human papillomavirus. Am J Surg Pathol, 2011; 35(5): 633-46.
  • 7. Sedlis A, Bundy BN, Rotman MZ, Lentz SS, Muderspach LI, Zaino RJ. A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage 1B carcinoma of the cervix aft er radical hysterectomy and pelvic lymphadenectomy: A Gynecologic Oncology Group Study. Gynecol Oncol 1999; 73:177-83.
Türk Jinekolojik Onkoloji Dergisi-Cover
  • ISSN: 2148-5372
  • Başlangıç: 2014
  • Yayıncı: Türk Jinekolojik Onkoloji Derneği
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