Amaç: Kliniğimizde gestasyonel trofoblastik hastalık tanısı alan, tedavi ve takipleri yapılan hastaların değerlendirilmesi.Materyal ve Metot: 1.1.1997-1.4.2004 tarihleri arasında Selçuk Üniversitesi Meram Tıp Fakültesi Kadın Hastalıkları ve Doğum Anabilim Dalında tanı konulup tedavi ve takipleri yapılan hastalar retrospektif olarak değerlendirildi.Bulgular: Gestasyonel trofoblastik hastalıklı 67 hastadan 42 (%62)sinde komplet mol hidatiform, 8 (%11)inde parsiyel mol 13 (%19)ünde invaziv mol, 4 (%5)ünde koryokarsinom tespit edildi. Primer tedavi olarak 50 hastaya vakum küretaj uygulandı. 40 yaşın üzerinde olan ve invaziv mol tanısı alan 6 hastadan 5 tanesine total abdominal histerektomi+bilateral salpingoooferektomi uygulanırken 1 tanesine vaginal histerektomi uygulandı. İnvazif mollü 9 hastaya ve koryokarsinomlu 4 hastaya kemoterapi verildi. Tüm hastalar seri serum β-hCG seviyeleri ile takip edildi.Sonuç: Gestasyonel trofoblastik hastalıklı olgularda erken tanı, yeterli tedavi ve sıkı takip başarılı sonuçların alınmasını sağlar.

Objective: To evaluate the patients who were diagnosed as gestational trophoblastic disease and get the treatment and the follow up modalities in our clinic. Materials and Methods: The patients who had been diagnosed and treated and followed-up in the Selcuk University, Faculty of Meram Medicine, Department of Obstetrics and Gynecology between 1.1.1997-1.04.2004 have been evaluated retrospectively. Results: In 42 of (%62) 67 patients with gestational trophoblastic disease complete mole hydatiform, in 8 (%11) partial mole, in 13 patients (%19) invasive mole, and in 4 (%5) of the patients choriocarcinoma was detected. Vacuum curettage was applied to 50 patients as primary treatment modality. Five total abdominal hysterectomy+bilateral salpingoopherectomy and 1 vaginal hysterectomy were applied to 6 patient who are over 40 years old and with invasive mole diagnosis and chemothrapy was given to 9 patients with invasive mole and 4 patients with choriocarcinoma. All patients were followed up by serial serum β-hCG levels. Conclusion: Early diagnosis, appropriate treatment and careful follow-up leads to successful result in gestational trophoblastic disease.