İlhan PAŞAOĞLU, Oktay KORUN, Şafak ALPAT, Sevgen ÖNDER, Rıza DOĞAN, Metin DEMİRCİN, Mustafa YILMAZ

Perikardiyal adezyonları önlemede bariyer yöntemlerin kombine kullanımı: Her zaman daha iyi midir?

Amaç: Bu çalışmada bir tavşan modeli üzerinde perikard kapatılması, genişletilmiş politetrafloroetilen (ePTFE) membran ve rezorbe edilebilen adezyon bariyerinin (REPEL-CV®) kombine ya da ayrı ayrı kullanımının perikardiyal adezyonlar üzerine etkileri araştırıldı.Çalışma planı: Otuz tavşan altı gruba randomize edildi: kontrol, perikard, genişletilmiş politetrafloroetilen, rezorbe edilebilen membran, genişletilmiş politetrafloroetilen + rezorbe edilebilen membran ve perikard + rezorbe edilebilen membran. Ameliyat sonrası beşinci haftada yapışıklıkların yoğunluğu kalitatif bir derecelendirme sistemi kullanılarak değerlendirildi ve histolojik örnekler incelendi. Bulgular: Rezorbe edilebilen membran grubunun tenasite skorları kontrol, perikard ve genişletilmiş politetrafloroetilen gruplarına kıyasla, anlamlı düzeyde düşük bulundu (p

Combined use of barrier methods to prevent pericardial adhesions: Is it always better?

Background: This study aims to investigate the effects of combined and individual use of pericardial closure, expanded polytetrafluoroethylene membrane and resorbable adhesion barrier (REPEL-CV®) on pericardial adhesions on a rabbit model.Methods: Thirty rabbits were randomly assigned to six groups: control, pericardium, expanded polytetrafluoroethylene, resorbable membrane, expanded polytetrafluoroethylene + resorbable membrane, and pericardium + resorbable membrane. At the postoperative five weeks, the tenacity of the adhesions was evaluated using a qualitative grading system, and histological specimens were examined.Results: Resorbable membrane group had significantly lower tenacity scores, compared to the control, pericardium, and expanded polytetrafluoroethylene groups (p

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