Derin ven trombozunda güncel tedavi yaklaşımları

Venöz tromboembolizm veya en sık görülen formuyla derin ven trombozu (DVT) önemli bir mortalite ve morbidite nedenidir. Gelişmiş ülkelerde ileri yaşlarda %1 oranında görülen bu hastalık, en sık alt ekstremite ve pelvik venlerinden kaynaklanmaktadır. Pulmoner tromboembolilerin (PTE) yaklaşık %70’inde DVT olması, DVT olgularının yarısından fazlasında PTE gelişmesi nedeniyle, bu ikisi tek bir antite olarak kabul edilebilir. Klasik DVT tedavisinde uyguladığımız yöntemler, zaman içinde yeni tedavi seçeneklerinin ortaya çıkması ve farklı klinik uygulamaların karşılaştırmalı sonuçlarının yayınlanması ile sürekli olarak değişmektedir. Bu derlemede, DVT’nin güncel kılavuz bilgileri ışığında incelenmesi amaçlandı. Zamanında ve etkin bir şekilde yapılan tedavi yaklaşımı ile DVT’den kaynaklanan mortalite ve morbiditeyi en aza indirgemek mümkündür.

Current treatment strategies in deep vein thrombosis

Venous thromboembolism or commonly known as deep venous thrombosis (DVT) is an important cause of mortality and morbidity. In advanced age group, it has an incidence of up to 1% in developed countries. Deep venous thrombosis most frequently arises from the lower extremity and pelvic veins. Since DVT can be found in about 70% of cases with pulmonary thromboembolism (PTE), and about half of the DVT cases develop PTE, these two can be regarded as a single clinicopathologic entity. The methods used in the treatment of classical DVT undergo alterations in parallel with the evolution of alternative treatment options and publication of comparative results of clinical studies. In this article, we aimed to review DVT in the light of current guidelines. A timely and correct treatment approach is essential to minimize mortality and morbidity rates associated with DVT.

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