Lung cancer associated with a single simultaneous solitary metastatic lesion in stomach: A case report with the review of literature
Mideye ait metastatik tümörler oldukça nadirdir. Pek çok doku neoplazmının mideye metastaz yapabileceği bildirilmiş olsa da, akciğer kanseri nadir bir metastaz nedenidir. Burada, ilk başvuru bulgusu vena kava sendromu olan 46 yaşındaki erkek olguyu sunmayı amaçladık. Primer akciğer tümörün histopatolojisi bilgisayarlı tomografi eşliğinde alınan biyopsi ile küçük hücreli dışı akciğer kanseri olarak rapor edildi. Takipleri sırasında gastrik yakınmaları olan hastaya üst gastrointestinal sistem endoskopisi uygulandı. Endoskopi bulguları primer skuamöz hücreli kanserin metastazını teyit etti ve yapılan taramaları da farklı uzak organ metastazının olmadığını, gastrik bölgenin tek bir metastaz odağı olduğunu işaret etti.
Midede izole, eş zamanlı metastatik lezyon ile seyreden akciğer kanseri: Literatür eşliğinde olgu sunumu
Metastatic tumors of the stomach are rare. Although neoplasms from almost every tissue have been reported to metastasize to the stomach, lung cancer is a rare cause. We report the case of 46-years-old man presented with superior Vena Cava syndrome. Histopathological diagnosis was non-small cell lung cancer with computed tomography-guided needle biopsy of lung. Since gastric symptoms occured during follow up of patient, upper gastrointestinal endoscopy performed. Upper gastrointestinal endoscopy and biopsy showed metastasis of stomach secondary to primary squamous cell lung cancer and additionally lack of another distant site metastasis indicated that gastric region was the single site of tumor spread.
___
- 1. Garwood RA, Sawyer MD, Ladesma EJ, et al. A case and review of bowel perforation secondary to metastatic lung cancer. The American Surgeon 2005; 71: 110-6.
- 2. The guideline of lung cancer diagnosis and treatment. Turkish Thoracic Journal 2006; (Suppl 2): 1-29.
- 3. Yamamoto M, Matsuzaki, Kusumoto H, et al. Gastric metastasis from lung carcinoma: Case report. Hepato-Gastroenterology 2002; 49: 363-5.
- 4. Stenbygaard LE, Sorensen JB, Larsen H, et al. Metastatic patern in non-resectable non-small cell lung cancer. Acta Oncol 1999; 38: 993-8.
- 5. McNeill P, Wagman LD, Neifeld JP. Small bowel metastases from primary carcinoma of the lung. Cancer 1987; 59: 1486-9.
- 6. Yang CJ, Hwang JJ, Kang WY, et al. Gastrointestinal metastasis of primary lung carcinoma: Clinical presentations and outcome. Lung Cancer 2006; 54: 319-23.
- 7. Caravelli JF, Sklarin NT, Panicek DM, et al. Metastatic lobular carcinoma of the breast: Patterns of spread in the chest, abdomen and pelvis on CT. Am J Roentgenol 2000; 175: 795-800.
- 8. Blecker D, Abraham S, Furth E, et al. Melanoma in the gastrointestinal tract. Am J Gastroenterol 1999; 94: 3427-33.
- 9. Suzaki N, Hiraki A, Ueaka H, et al. Gastric perforation due to metastasis from lung carcinoma of the lung. Anticancer Research 2002; 22: 1209-12.
- 10. Fletcher MS. Gastric perforation secondary to metastatic carcinoma of the lung: A case report. Cancer 1980; 46: 1879-82.
- 11. Schmidt G. Gastric perforation secondary to metastatic bronchogenic carcinoma: A case report. Hepatogastroenterol 1985; 32: 103-5.
- 12. Maeda J, Miyake M, Tokita K, et al. Small cell lung cancer with extensive cutaneus and gastric metastases. Internal Medicine 1992; 31: 1325-8.
- 13. Casella G, Di Bella C, Cambareri AR, et al. Gastric metastasis by lung small cell carcinoma. World Journal Gastroenterology 2006; 12: 4096-7.
- 14. Radin DR, Halls JM. Cavitating metastases of the stomach and duodenum. Comput Tomogr 1987; 11: 83-7.
- 15. Lunch P, Green L, Jordan PH. Hepatocellular carcinoma metastatic to the stomach presenting as bleeding multiple craterogenic ulcers. Am J Gastoenterol 1989; 84: 653-5.
- 16. Altintas E, Sezgin O, Uyar B. Accute upper gastrointestinal bleeding due to metastatic lung cancer: An unusual case. Yonsei Med J 2006: 276-7.
- 17. Kadakia SC, Parker A, Canales L. Metastatic tumors to the upper gastrointestinal tract endoscopic experience. Am J Gastroenterol 1992; 87: 1418-23.
- 18. Kim HS, Jang WI, Hong HS, et al. Metastatic involvement of the stomach secondary to lung carcinoma. Journal Korean Medical Science 1993; 8: 24-9.
- 19. Green LK. Hematogenous metastases to the stomach. A review of 67 cases. Cancer 1990; 65: 168-71.
- 20. Wu MH, Lin MT, Lee PH. Clinicopathological study of gastric metastases. World J Surg 2007; 31: 132-6.