A case of leucocytoclastic vasculitis due to T-cell rich B-cell lymphoma

Lökositoklastik vaskülit, etyolojisinde çeşitli faktörlerin sorumlu olduğu heterojen bir hastalık grubudur. Malignitesi olan hastalarda paraneoplastik bir fenomen olarak görülebilir. Bu yazıda derinin lökositoklastik vaskülitine bağlı sırt, abdomen, göğüs duvarı ve ekstremitelerinde diffüz, plak tarzında döküntüleri olan 68 yaşında T hücreden zengin B hücreli non-Hodgkin lenfoma tanısı konmuş bir erkek hasta sunulmaktadır. Hastanın deri bulguları kemoterapi ve mini-mantle radyoterapi ile primer hastalığın remisyonu sonucunda tamamen düzeldi. Malignitesi olan hastalarda deri döküntüleri, primer tümör tutulumu ya da vaskülite sekonder olabilmektedir. Etkilenen dokunun histopatolojik incelemesi sekonder vaskülitleri primer tümör metastazından ayrımında yardımcıdır.

Anahtar Kelimeler:

Lenfom, Hodgkin dışı, Paraneoplastik sendromlar, Vaskülit, Lenfom, B-hücreli, Yaşlı, Erkek

T hücreden zengin B hücreli lenfomaya bağlı lökositoklastik vaskulitli bir olgu

Leucocytoclastic vasculitis is a heterogeneous group of disorders with various factors responsible in its etiology. It can be observed as a paraneoplastic phenomenon in patients with malignancies. Here we report a 68 year old male with T cell rich B cell non- Hodgkin lymphoma, who had diffuse plaque-type rashes on his back, abdomen, chest wall, and extremities due to leucocytoclastic vasculitis of the skin. He received chemotherapy and mini mantle radiotherapy. Cutaneous findings of the patient resolved completely with the remission of the primary disease. Skin rashes in patients with malignancies may be due to primary tumor involvement or secondary to vasculitis. Histopathological examination of affected tissue specimen is helpful to distinguish secondary vasculitis from primary tumor metastasis.

Keywords:

Lymphoma, Non-Hodgkin, Paraneoplastic Syndromes, Vasculitis, Lymphoma, B-Cell, Aged, Male,

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