Parotis Bezi Kitlelerinin Sistemik İnflamatuvar Parametrelerle İlişkisi
Amaç: Son yıllarda yapılan çalışmalar kanser ve inflamatuvar yanıt arasında bir ilişki olduğunu
göstermiştir. Bu çalışmada inflamatuvar parametrelerden nötrofil/lenfosit oranı, trombosit/
lenfosit oranı ve sistemik immün inflamasyon indeksinin parotise ait kitlelerin ayırıcı tanısında
kullanılıp kullanılamayacağını incelemeyi amaçladık.
Gereç ve Yöntem: Bu retrospektif çalışmamızda Dicle Üniversitesi Tıp Fakültesi Kulak Burun
Boğaz Polikliniği’ne parotiste kitle ile başvurmuş ve opere edilmiş toplam 100 hasta ile 70
sağlıklı birey kontrol grubu olarak çalışmaya alınmıştır. Hastaların 18’inin malign patolojisi
varken 82’sinin patolojisi benign idi. Malign hasta grubu, benign hasta grubu ve kontrol grubu
hemogram tetkikinden oranlanarak elde edilen nötrofil/lenfosit oranı, trombosit/lenfosit oranı
ve sistemik immün inflamatuvar indeks parametreleri açısından karşılaştırıldı.
Bulgular: Sistemik immün inflamatuvar indeks ve nötrofil/lenfosit oranı yönünden üç grup
arasında anlamlı fark varken (p=0.006, p=0.000) trombosit/lenfosit oranı açısından gruplar arasında
anlamlı farklılık gözlenmedi (p=0.285). Gruplar sistemik immün inflamatuvar indeks ve
nötrofil/lenfosit oranı açısından ikili olarak karşılaştırıldığında, kontrol grubu ile benign hasta
grubu arasında (p
Relationship of Parotid Gland Masses with Systemic Inflammatory Parameters
Objective: Studies in recent years have shown a relationship between cancer and inflammatory
response. In this study, we aimed to investigate whether neutrophil/lymphocyte ratio, platelet/
lymphocyte ratio and systemic immune inflammation index can be used in the differential diagnosis
of parotid masses.
Materials and Methods: In this retrospective study, 100 patients who came to Dicle University
Faculty of Medicine Otorhinolaryngology outpatient clinic with a parotid mass and were operated
were determined as the study group. 70 healthy individuals were determined as the control group. While 18 of the patients had malignant pathology, 82 of them were benign. Malignant patient group,
benign patient group and control group were compared in terms of neutrophil/lymphocyte ratio, platelet/
lymphocyte ratio and systemic immune inflammation index parameters obtained from the hemogram examination.
Results: While there was a significant difference between the three groups in terms of systemic immune
inflammation index and neutrophil/lymphocyte ratio (p=0.006, p=0.000), no significant difference was observed
between the groups in terms of platelet/lymphocyte ratio (p=0.285). When the groups were compared
in terms of systemic immune inflammation index and neutrophil/lymphocyte ratio in pairs, there was
a significant difference between control group and benign patient group (p
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