ABSTRACT The purpose of this research was to analyze the physico-chemical qualities of drinking and ground waters in the Şanlıurfa and Adıyaman provinces of Turkey. The water quality parameters were pH, calcium (Ca++), magnesium (Mg++), sodium (Na+), potassium (K+), electrical conductivity (EC), sodium absorption rate (SAR), chlorine (Cl-), and bicarbonate (HCO3-). The International Organisation for Standardization (ISO) and Turkish Standard (TS) methods were used in this study. A total of 193 water samples were collected from 13 districts.  The cations were analyzed using ICP-OES. According to the physico-chemical analyses of the samples, pH levels were within the standard levels and the mean values of EC, Ca++, Mg++, Na+, K+, Cl-, HCO3-, and SAR were 419.20±138.88, 2.703±4.825 me/L, 1.371±0.875 me/L, 1.058±1.285 me/L, 0.281±0.907 me /L, 1.115±0.640 me/L, 3.45±1.83 me/L and 0.722±0.369, respectively. The analyses revealed that the quality of the water investigated was within acceptable limits, therefore, it is deemed appropriate for an evaluation as drinking and ground water.  Key words: Water, ICP-OES, pysico-chemical qualities, Şanlıurfa, Adıyaman