Raşit CEVİZCİ, Barış KARAKULLUKÇU, Michiel W.m. VAN DEN BREKEL, Alfons J. BALM

Tipik larenks karsinoid tümörünün lazer eksizyonu: Olgu sunumu

Larenksin nöroendokrin karsinomları nadir görül- mekle birlikte değişken biyolojik davranışları nede- niyle tedavi ve prognozları farklıdır. Bunlar arasın- da tipik karsinoid tümörler en sık görülen tipidir. Larenksin tipik karsinoid tümörünün gidişatı atipik karsinoid tümöre ve küçük hücreli karsinoma göre daha iyidir. Konservatif cerrahi tercih edilen tedavi yöntemidir. Transoral CO2 lazer cerrahisi, fonksiyo- nel sonuçları ve morbiditenin düşük olması nedeniy- le uygun olgularda iyi bir seçenek olabilir. Bu yazıda, yutkunurken boğazında kitle hissi yakınması ile başvuran 71 yaşında kadın hasta sunuldu. Fiberoptik muayenesinde sağ ariepiglottik pilika yerleşimli kitle ile karşılaşıldı ve alınan biyopsi sonucu tipik karsinoid tümör olarak bildirildi. Bu olgu sunumunda larenks yerleşimli tipik karsinoid tümörün CO2 lazer ile çıkarılması bildirildi

Anahtar Kelimeler:

Karsinoid tümör/tanı/cerrahi, larenks tümörleri, lazer tedavisi, paragangliyom/tanı/cerrahi

Laser excision of a typical carcinoid tumor of the larynx: a case report

Neuroendocrine carcinomas of the larynx include a range of rare tumors which have variable biologic behavior, affecting treatment and prognosis. Among these, typical carcinoid tumors are the least common type. Prognosis of typical carcinoid tumor is better than atypical carcinoid tumor and small cell carcinoma of the larynx. Conservation surgery is the preferred treatment modality. Transoral CO2 laser surgery can be a good alternative for appropriate cases because of the functional results and less morbidity. In this article, a 71-year-old female presented with complaints of feeling a mass during swallowing. Fiberoptic examination of the larynx revealed a mass located on the right aryepiglottic fold and biopsy revealed the tumor as a typical carcinoid tumor. We describe CO2 laser excision of a typical carcinoid tumor of the larynx in this case report.

Keywords:

Carcinoid tumor/diagnosis/surgery, laryngeal neoplasms, laser therapy, paraganglioma/diagnosis/ surgery,

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Ferlito A, Devaney KO, Rinaldo A. Neuroendocrine neoplasms of the larynx: advances in identifica- tion, understanding, and management. Oral Oncol 2006;42:770-88.
Micozkadıoğlu SD, Özer C, Bolat F. Larenksin atipik karsinoid tümörü: Olgu sunumu. Turk Arch Otolaryngol 2009;47:48-52.
Ferlito A, Barnes L, Rinaldo A, Gnepp DR, Milroy CM. A review of neuroendocrine neoplasms of the larynx: update on diagnosis and treatment. J Laryngol Otol 1998;112:827-34.
Bapat U, Mackinnon NA, Spencer MG. Carcinoid tumours of the larynx. Eur Arch Otorhinolaryngol 2005;262:194-7.
Ferlito A, Rinaldo A. The spectrum of endocrinocarci- nomas of the larynx. Oral Oncol 2005;41:878-83.
Ferlito A, Silver CE, Bradford CR, Rinaldo A. Neuroendocrine neoplasms of the larynx: an over- view. Head Neck 2009;31:1634-46.
Soga J, Ferlito A, Rinaldo A. Endocrinocarcinomas (carcinoids and their variants) of the larynx: a com- parative consideration with those of other sites. Oral Oncol 2004;40:668-72.
Soga J. Carcinoids and their variant endocrinomas. An analysis of 11842 reported cases. J Exp Clin Cancer Res 2003;22:517-30.
Chang KP, Lee LY, Yeh AR, Dai TS, Hao SP. Endoscopic CO2 laser surgery for an atypical carcinoid tumor of the epiglottis masquerading as a supraglottic cyst. Head Neck 2005;27:1004-7.
Batsakis JG, el-Naggar AK, Luna MA. Neuroendocrine tumors of larynx. Ann Otol Rhinol Laryngol 1992;101:710-4.
Karatzanis AD, Psychogios G, Zenk J, Waldfahrer F, Hornung J, Velegrakis GA, et al. Evaluation of avail- able surgical management options for early supraglot- tic cancer. Head Neck 2010;32:1048-55.
Hinni ML, Salassa JR, Grant DG, Pearson BW, Hayden RE, Martin A, et al. Transoral laser microsurgery for advanced laryngeal cancer. Arch Otolaryngol Head Neck Surg 2007;133:1198-204.
Peretti G, Piazza C, Cocco D, De Benedetto L, Del Bon F, Redaelli De Zinis LO, et al. Transoral CO(2) laser treatment for T(is)-T(3) glottic cancer: the University of Brescia experience on 595 patients. Head Neck 2010;32:977-83.