Yezdan FIRAT, Can KOÇ, Işıl OLCAY, Adin SELÇUK, Ahmet Kemal FIRAT, Cafer ÖZDEM

10425

Rekürren sekretuar otitis media'lı erişkin hastalarda atopi insidansının Phadiatop® ile araştırılması

Amaç: Rekürren sekretuar otitis mediası SOM olanerişkin hastalarda, göreceli yeni bir yöntem olan Phadiatop®ile atopi varlığı araştırıldı; yöntemin duyarlılığı,özgüllüğü ve tarama testi olarak kullanılabilirliği incelendi.Hastalar ve Yöntemler: Çalışmaya rekürren SOM tanısı alan 84 hasta alındı. Hastalarda öykü, laboratuvarbulguları, deri testi ve total IgE düzeyi incelendi. Enaz bir deri testi pozitif ve/veya total IgE sonucu yüksek, öyküsü pozitif olan hastalar atopik olarak kabuledildi.Bulgular: Belirlenen kriterlere göre rekürren SOM’uolan 84 hastanın 31’inde atopi saptandı. Atopik olmayan 53 hastanın hepsinde ve bir atopik hastada Phadiatop®değerleri negatif bulundu. Otuz bir atopik hastanın 30’unda Phadiatop®değerleri pozitif bulundu Özgünlük:1.00, duyarlılık: 0.97, pozitif tahmin değeri: 1.00,negatif tahmin değeri: 0.98 .Sonuç: Bu bulgular, rekürren SOM’u olan hastalardaatopinin saptanması için Phadiatop®’un etkin bir taramatesti olduğunu göstermektedir
Anahtar Kelimeler:

Secretuar otitis media, atopi, rekürren, Phadiatop®

The incidence of atopy in adults with recurrent secretory otitis media: screening with Phadiatop®

Objectives: This is a preliminary report of a relatively new method: Phadiatop®, in screening atopic adult patients with recurrent secretory otitis media SOM .The sensitivity and specificity, and its use in atopic adult patients with recurrent SOM are described.Patients and Methods: Eighty four patients 54 females, 30 males; mean age 36.7; range 19 to 62 years who were diagnosed as recurrent SOM were included in the study.The patients were evaluated with detailed history, labora- tory tests, skin-prick test and total IgE. Patients with at least one positive skin-prick test and/or high total IgE with a positive history were considered to be in atopic status.Results: According to certain criteria, atopy was detected in 31 of the 84 patients. Negative Phadiatop® values were found on ali of 53 non-atopic patients as well as in one atopic patient. Among 31 patients having atopy, 30 of them shovved positive Phadiatop® values Specificity: 1.00, sensitivity: 0.97, predictive value, positive: 1.00, predictive value, negative: 0.98 .Conclusion: These results indicate that Phadiatop® is an effective test to detect atopy in patients with recurrent SOM.
Keywords:

Secretory otitis media, atopy, recurrenti, Phadiatop,

PDF

___

  • Bernstein JM. Otitis media with effusion. In: Ballenger JJ, editor. Disease of the nose, throat, ear, head and neck. 14th ed. Philadelphia: Lea and Febiqer; 1991. p. 154-61.
  • Özkarakaş H, Erol Hİ, Özcan A, Güngör A, Candan H, Poyrazoğlu E. Efüzyonlu otitis media’da efüzyonun immunokimyasal değerlendirmesi ve etyolojik neden- lere yaklaşım. Türk Otolarengoloji Arşivi 1993;31:139- 41.
  • Eriksson NE. Allergy screening with Phadiatop and CAP Phadiatop in combination with a questionnaire in adults with asthma and rhinitis. Allergy 1990;45:285- 92.
  • Miller AJ, Gianoli GJ. Eustachian tube dysfunction. J La State Med Soc 1996;148:329-33.
  • Bunne M, Magnuson B, Falk B, Hellstrom S. Eustachian tube function varies over time in children with secretory otitis media. Acta Otolaryngol 2000;120:716-23.
  • Bartolozzi G, Sacchetti A, Scarane P, Becherucci P. Natural history of otitis media with effusion in chil- dren under six years of age. Adv Otorhinolaryngol 1992;47:281-3.
  • Bluestone CD, Beery QC, Paradise JL. Audiometry and tympanometry in relation to middle ear effusions in children. Laryngoscope 1973;83:594-604.
  • Fiellau-Nikolajsen M. Tympanometry and secretory otitis media. Observations on diagnosis, epidemiology, treatment, and prevention in prospective cohort stud- ies of three-year-old children. Acta Otolaryngol Suppl 1983;394:1-73.
  • Nsouli TM, Nsouli SM, Linde RE, O’Mara F, Scanlon RT, Bellanti JA. Role of food allergy in serous otitis media. Ann Allergy 1994;73:215-9.
  • Ackerman MN, Friedman RA, Doyle WJ, Bluestone CD, Fireman P. Antigen-induced eustachian tube obstruction: an intranasal provocative challenge test. J Allergy Clin Immunol 1984;73(5 Pt 1):604-9.
  • Terr AI. The atopic diseases. In: Daniel P, editor. Basic and clinical immunology. 8th ed. Connecticut: Appleton and Lange; 1994. p. 327-45.
  • Reichtmeier WJ. Basic allergy and immunology. In: Cummings CW, editor. Otolaryngology head and neck surgery. 2nd ed. St Louis: Mosby Company; 1993. p. 243-76.
  • Sin A, Kose S, Terzioglu E, Kokuludag A, Sebik F, Kabakci T. Prevalence of atopy in young healthy pop- ulation, in Izmir, Turkey. Allergol Immunopathol (Madr) 1997;25:80-4.
  • Bergmann RL, Forster J, Schulz J, Bergmann KE, Bauer CP, Wahn U. Atopic family history. Validation of instruments in a multicenter cohort study. Pediatr Allergy Immunol 1993;4:130-5.
  • Fireman P. Otitis media and its relationship to allergy. Pediatr Clin North Am 1988;35:1075-90.
  • Skoner DP, Doyle WJ, Chamovitz AH, Fireman P. Eustachian tube obstruction after intranasal challenge with house dust mite. Arch Otolaryngol Head Neck Surg 1986;112:840-2.
  • İlhan F, Akbulut H, Coşkun BK. Atopik dermatitli hastalarda total IgE değerleri. Fırat Tıp Dergisi 2005;10:10-1.
  • Prevalence of asthma and asthma symptoms in a gen- eral population sample from northern Italy. European Community Respiratory Health Survey--Italy. Allergy 1995;50:755-9.
  • National Heart, Lung, and Blood Institute, National Asthma Education and Prevention Program. Expert Panel Report: guidelines for the diagnosis and man- agement of asthma. Bethesda MD: US Department of Health and Human Services, National Institutes of Health; 1991. No. 91-3042.
  • Bos JD, Van Leent EJ, Sillevis Smitt JH. The millennium criteria for the diagnosis of atopic dermatitis. Exp Dermatol 1998;7:132-8.
  • Bruijnzeel-Koomen C, Ortolani C, Aas K, Bindslev- Jensen C, Bjorksten B, Moneret-Vautrin D, et al. Adverse reactions to food. European Academy of Allergology and Clinical Immunology Subcommittee. Allergy 1995;50:623-35.
  • Lim KG, Weller PF. Eosinophilia and eosinophil-relat- ed disorders. In: Middleton E, Reed R, Ellis EF, editors. Allergy: Principles and practice. 5th ed. St. Louis: Mosby; 1998. p. 783-98.
  • Mullarkey MF. Eosinophilic nonallergic rhinitis. J Allergy Clin Immunol 1988;82(5 Pt 2):941-9.
  • Sapan N, Tunalı Ş. Atopinin in vitro tanısında Phadiatop. Uludağ Üniv. Tıp Fak. Derg 1991;18:51-4.
  • Sönmez E, Tanaç R. Evaluation of phadiatop for aller- gy diagnosis and correlation with other diagnostic tests. Ege Tıp Dergisi 1993;3:109-12.
  • Ahlstedt S. Understanding the usefulness of specific IgE blood tests in allergy. Clin Exp Allergy 2002;32:11- 6.
The Turkish Journal of Ear Nose and Throat-Cover
  • ISSN: 2602-4837
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 1991
  • Yayıncı: İstanbul Üniversitesi
Arşiv
Sayıdaki Diğer Makaleler

Maksiller ve etmoid sinüslerden izole edilen Streptokok pnömoni, Streptokok viridans ve A grubu hemolitik Streptokok'larm antibiyotik dirençleri

Erol KELEŞ, Murat ARAL, Hayrettin Cengiz ALPAY

Alt konkadan kaynaklanan nazal polipozisi taklit eden koanal polip

Murat YARIKTAŞ, Harun DOĞRU, Fehmi DÖNER, Mustafa TÜZ, Hasan YASAN

Rekürren sekretuar otitis media'lı erişkin hastalarda atopi insidansının Phadiatop® ile araştırılması

Yezdan FIRAT, Can KOÇ, Işıl OLCAY, Adin SELÇUK, Ahmet Kemal FIRAT, Cafer ÖZDEM

Timpanik membran greftlemesinde sirkümferensiyel subanüler yöntem: İlk sonuçlar

Mustafa Cenk ECEVİT, Ataman GÜNERİ, Taner Kemal ERDAĞ