Orta kulak mukozasının primer malign melanomu: Olgu sunumu

Orta kulak ve mastoid kavite mukozasının malign melanoma bağlı primer tutulumu nadirdir. Sol ku- lakta ağrı, dolgunluk ve işitme kaybı yakınmalarıy- la başvuran 81 yaşındaki kadın hastanın otosko- pik muayenesinde mor renkli, vasküler görünüm- de kitlenin sol dış kulak yolunu tıkadığı görüldü. Bilgisayarlı tomografide yumuşak doku dansite- sindeki kitlenin orta kulak ve mastoid kaviteyi dol- durduğu, mastoid korteksi erode ederek dış kulak yolunun medial ve orta kısımlarını invaze ettiği görüldü. Kitleden alınan biyopsi sonucu malign melanom olarak bildirildi. Hastaya subtotal tempo- ral kemik rezeksiyonuna ek olarak radikal boyun diseksiyonu uygulandı ve ameliyat sonrası dö- nemde dakarbazin verildi. Temporal kemikten kaynaklanan tümörlerin ayırıcı tanısında malign melanomdan şüphelenmek erken tanıya olanak sağlamaktadır

Primary malignant melanoma of the middle ear mucosa: a case report

Primary involvement of the middle ear and mastoid mucosa by malignant melanoma MM has been rarely reported. We report an 81-year-old Caucasian woman presenting with otalgia, left-sided aural fullness, and hearing loss. Otoscopic examination revealed a purple coloured polyp that appeared to be vascular and occu- py left external auditory canal EAC . The computed tomography scanning showed a mass in soft tissue density, filling the tympanic and the mastoid cavities, eroding the mastoid cortex, and invading medial and Central parts of EAC. A biopsy was performed with the diagnosis of MM. The patient undervvent subtotal tem- poral bone resection with radical neck dissection.Dacarbazine was given postoperatively. The case pre- sented herein emphasizes the need to be aware that MMs can arise in the middle ear and mastoid cavity. An index of suspicion in the differential diagnosis of tem- poral bone tumours is necessary for early recognition.

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  • Langman A, Yarington T, Patterson SD. Malignant melanoma of the external auditory canal. Otolaryngol Head Neck Surg 1996;114:645-8.
  • McKenna EL Jr, Holmes WF, Harwick R. Primary melanoma of the middle ear. Laryngoscope 1984;94(11 Pt 1):1459-60.
  • Uchida M, Matsunami T. Malignant amelanotic melanoma of the middle ear. Arch Otolaryngol Head Neck Surg 2001;127:1126-8.
  • Sherman IW, Swift AC, Haqqani MT. Primary mucos- al malignant melanoma of the middle ear. J Laryngol Otol 1991;105:1061-4.
  • Beaver ME, Chang CYJ. Melanoma. In: Jackler RK, Driscoll CLW, editors. Tumors of the ear and the tem- poral bone. Philadelphia: Lippincott Williams & Wilkins, 2000. p. 56-66.
  • Manolidis S, Donald PJ. Malignant mucosal melanoma of the head and neck: review of the literature and report of 14 patients. Cancer 1997;80:1373-86.
  • Oueslati Z, Touati S, Gritli S, el-May A, Benna F, Boussen H, et al. Mucous malignant melanoma of the neck and face. Experience at the Salah Azaiz Institute (Tunis). Rev Laryngol Otol Rhinol (Bord) 2001;122:237- 40. [Abstract]
  • Urpegui Garcia A, Lahoz Zamarro T, Muniesa Soriano JA, Valles Varela H, Martinez Subias J, Sancho Serrano E, et al. Malignant melanoma of the middle ear, a rare site. Acta Otorrinolaringol Esp 1999;50:559-62. [Abstract]
  • Banerjee A, Meikle D. Malignant melanoma of the middle ear. J Laryngol Otol 1992;106:581.
  • Kagan AR, Stechel RJ, Allan M. Diagnostic oncology case study. AJR Am J Roentgenol 1982;138:943-4.
  • Muir CS, Nectoux J. Descriptive epidemiology of malignant neoplasms of nose, nasal cavities, middle ear and accessory sinuses. Clin Otolaryngol 1980;5:195-211.
  • Leonetti JP, Marzo SJ. Malignancy of the temporal bone. Otolaryngol Clin North Am 2002;35:405-10.
  • Wagner JD, Park HM, Coleman JJ 3rd, Love C, Hayes JT. Cervical sentinel lymph node biopsy for melanomas of the head and neck and upper thorax. Arch Otolaryngol Head Neck Surg 2000;126:313-21.