Sedat AYDIN, Arif ŞANLI, Günay ATEŞ, Mehmet EKEN, Özlem ÇELEBİ

Alerjik rinitli hastalarda alerjik deri pozitifliği ile nazal smear'deki eozinofilinin karşılaştırılması

Amaç: Alerjik rinit tanısında kullanılan deri testi ile nazal smear’de saptanan eozinofilinin kullanılabilirli ği ve bu iki test arasındaki ilişkinin derecesi karşılaştırıldı.Hastalar ve Yöntemler: Çalışmaya klinik öyküyle nazal alerjiden şüphe edilen 41 hasta 16 erkek, 25 kadın; ort. yaş 35.17; dağılım 14-56 ve öyküsünde alerjiyle ilgili herhangi bir şikayeti olmayan 15 gönül lü 7 erkek, 8 kadın; ort. yaş 27.6; dağılım 16-40 alındı. Her iki gruba alerjik deri testi uygulandı. Na zal smearler alınıp ışık mikroskobu altında değerlen dirildi.Bulgular: Çalışma grubundaki hastalarda, deri testinin pozitiflik oranı %73.2 iken kontrol grubunda bu oran %20 idi. Bununla birlikte hastaların %73.2 ve kontrol grubunun %13.3’ünde nazal smearde eozi- nofili saptandı. Her ne kadar alerjik deri testi ile nazal smear arasında %25.5 oranında bir ilişki olsada alerjik deri testi ile nazal smear’de saptanan eozino- fili arasında istatistiksel olarak anlamlı bir ilişki yoktu.Sonuç: Alerjik deri testi ve nazal smearde saptanan eozinofili, klinik öykü ile ilişki göstermekle birlikte, bu iki test arasında istatistiksel olarak anlamlı bir ilişki bulunamadı.

Anahtar Kelimeler:

Alerjik rinit, alerjik deri testi, nazal smear, eozinofili

Comparison of nasal smear eosinophilia with skin prick test

Objectives: The aim of this study was to compare the usefulness of nasal smear eosinophilia with skin prick test for the diagnosis of allergic rhinitis and to deter- mine the degree of correlation between the tests.Patients and Methods: Forty-one patients 16 males, 25 females; mean age 35.17; range 14 to 56 years with a clinical history suggestive of nasal allergy and fifteen Controls 7 males, 8 females; mean age 27.6; range 16 to 40 years without any history of allergy were enrolled in this study. Skin sensitivity tests were applied in both groups. Nasal smear was examined by light microscopy.Results: A positive skin test reaction was demon- strated in 73.2% of the study group and 20% of the Controls whereas 73.2% of the patients and 13.3% of the Controls demonstrated significant nasal smear eosinophilia. There was 25.5% correlation between the skin prick test and nasal smear eosinophilia, although this was not statistically sig nificant.Conclusion: Both the skin prick test and the nasal smear eosinophilia showed correlation with the clin ical history but there was no statistically significant correlation between the two tests.

Keywords:

Allergic rhinitis, skin-prick test, nasal smear, eosinophilia,

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The Turkish Journal of Ear Nose and Throat-Cover

ISSN: 2602-4837
Yayın Aralığı: Yılda 4 Sayı
Başlangıç: 1991
Yayıncı: İstanbul Üniversitesi

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