Menopoz sonrası dönemde kadınlarda üst solunum yolu enfeksiyonları sıklığı ve egzersizin tükürük IgA sekresyonuna etkisi

Amaç: Menopoz sonrası dönemdeki Türk kadınlarındaüst solunum yolu enfeksiyonu ÜSYE tiplerini araştırmak ve orta düzeydeki aerobik egzersiz ile tükürük IgAsekresyonu ve ÜSYE arasındaki ilişkiyi incelemek.Olgular ve Yöntemler: On iki haftalık bu prospektif çalışmaya, gönüllü olarak katılmayı kabul eden, 45-65 yaşlarında, sağlıklı, sedanter yaşayan 90 kadın alındı. Kadınlar, ev içi veya dışında egzersiz yapan veya egzersiz yapmayan olmak üzere sayıca eşit üç gruba ayrıldı. Egzersizyapan kadınlara, haftada beş gün, günde 30 dakika süreli ev içi yürüme bandında veya dışarda, maksimal kalp hızının %60’ını geçmeyecek şekilde yürüme egzersizleriverildi. On iki haftalık sürede ÜSYE düşündüren semptomlar kaydedildi. Egzersiz yapmayan kadınlar haftalıktelefon konuşmalarıyla izlendi. Tüm katılanların çalışmaöncesi ve bitiminde tükürük IgA düzeyleri ölçüldü.Bulgular: Egzersiz yapan ve yapmayan kadınlar arasında, ÜSYE epizodlarının sayısı ve epizod başınaÜSYE semptomatolojisinin süresi açısından, egzersizgrupları lehine anlamlı farklılık görüldü. Ev içinde vedışında egzersiz yapanlar arasında bu açıdan farklılıkyoktu. Tükürük IgA düzeyleri gruplar arasında ve herbir grupta çalışma öncesi ve sonrasında farklılık göstermedi.Sonuç: Orta ağırlıkta aerobik egzersiz yapan sağlıklıpostmenopozal Türk kadınlarında daha az sayıda ÜSYE epizodu ve epizod başına daha kısa süren ÜSYEsemptomatolojisi görüldüğü ve egzersizin tükürük IgAkonsantrasyonuyla ilişkisi olmadığı sonucuna varıldı

The effect of exercise on salivary IgA levels and the incidence of upper respiratory tract infections in postmenopausal women

Objectives: To examine the patterns of upper respiratory tract infections URTI in postmenopausal Turkish women and the relationship of moderate aerobic exercise with secretion of salivary IgA and episodes of URTI.Materials and Methods: Ninety healthy, sedentary women at ages 45 to 65 years volunteered to participate in a 12-week prospective study. They were randomized to three groups equal in number: indoor exercise, outdoor exercise, and no exercise. The exercising women were supervised during 30 min indoor treadmill walk or outdoor track vvalking sessions during 5 days/week at 60% of their calculated maximal heart rate. During a 12-week exercise program, episodes suggestive of URTI were recorded.Non-exercising women were follovved with vveekly tele- phone calls. The salivary IgA levels were measured in ali the subjects before and at the end of the study.Results: There were significant differences betvveen the exercising and non-exercising women with respect to the number of URTI episodes and the length of URTI symp- tomatology per episode in favor of exercise. No signifi­ cant difference was found betvveen the indoor and out­ door exercising groups. The salivary IgA levels shovved no significant differences betvveen the three groups and vvithin each group.Conclusion: Moderate intensity aerobic exercise is associated vvith fevver episodes of URTI and fevver days of URTI symptomatology per episode in healthy post­ menopausal Turkish vvomen, but this does not seem to be related to salivary IgA concentrations.

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