Hiperlipideminin işitme fonksiyonu üzerine etkisi
Amaç: Hiperlipideminin iflitme fonksiyonu üzerine etkilerini değerlendirdik.Hastalar ve Yöntemler: Çalıflmaya hiperlipidemi tanısı konan 274 hasta alındı. Olguların hepsinde kulak zarı bulguları normaldi; gürültüye maruz kalma hikayesi yoktuve iflitme ile ilgili veya sistemik kronik bir hastalığı bulunmuyordu. Aynı ölçütlere sahip, serum lipid düzeyleri normal 60 kifliden 36 kadın, 24 erkek kontrol grubu oluflturuldu. Serum total kolesterol, trigliserid veçok düflük dansiteli lipoprotein VLDL düzeyleri yüksek olan ve normal lipid değerine sahip olgular dörtgruba ayrılarak iflitme fonksiyonları saf ses odyometriile değerlendirildi.Bulgular: Kontrol grubuna göre kadın hastalarda üç frekansta, erkek hastalarda ise altı frekansta iflitme ortalamalarında anlamlı yükselme görüldü p
Anahtar Kelimeler:
Odyometri, saf-ses, kolesterol/kan, iflitme/fizyoloji, iflitme kaybı, sensorinöral/etyoloji, hiperlipidemi/komplikasyon, trigliserid/kan
The effect of hyperlipidemia on hearing function
Objectives: We evaluated the effects of hyperlipi demia on hearing function.Patients and Methods: The study included 274 hyperlipidemic patients 176 females, 98 males; age range 35 to 60 years who manifested normal tym- panic membrane findings, no history of noise expo- sure, and chronic systemic or ear diseases. Sixty healthy subjects 36 females, 24 males with normal serum lipid levels were enrolled as Controls. Subjects who had elevated serum total cholesterol, triglyceride, and very low density lipoprotein VLDL levels, and normal lipid levels were divided into four groups and their hearing functions were analysed with pure-tone audiometry.Results: Evaluation of ali groups shovved significantly increased hearing levels at three frequencies in female patients, and at six frequencies in male patients p<0.05 . Significant increases in hearing lev els were observed both in females and males at 8000 Hz in three groups, at 6000 Hz in the VLDL group, and in males at 2000 Hz in the total cholesterol and VLDL groups p<0.05 . When both female and male patients were evaluated together, the largest difference was detected in the VLDL group at five frequencies.Conclusion: The findings of our study suggest that hyperlipidemia may have a role on the occurrence of sensorineural hearing loss.
Keywords:
Audiometry, pure-tone, cholesterol/blood, hearing/physiology, hearing loss, sensorineural/etiology, hyperlipidemia/complications, triglycerides/blood,
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- ISSN: 2602-4837
- Yayın Aralığı: Yılda 4 Sayı
- Başlangıç: 1991
- Yayıncı: İstanbul Üniversitesi
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