Alerjik rinitin değişken prevalansı ve prevalansı etkileyen risk faktörleri

Alerjik rinit burunda akıntı, hapşırık, kaşıntı ve tıkanıklık, sıklıkla konjonktival enjeksiyon ve gözde kaşınmayla karakterize olan burun mukozasının kronik enflamasyonu olarak tanımlanmaktadır. Çocukluk çağı alerjik rinit prevalansı dünya çapında hızlı bir artış göstermektedir. Ancak bölgeler arasında bariz farklar vardır, bu da alerjik rinitin gelişiminde değişen genetik ve çevresel etkenlere işaret etmektedir. Bölgesel bu fark, genetik yatkınlık yanında çevresel ve davranışsal faktörlerin hızlı değişimiyle meydana gelen ‘Batı tarzı diyet’ ve ‘Batılı yaşam tarzı’ ile esas olarak ilişkili bulunmuştur. Alerjik rinit gelişimine yol açan bazı ana ve potansiyel risk faktörleri halen net olarak bilinmemektedir. Bu derlemede, çoğu iyi bilinen ve bazı yeni ortaya çıkmış risk faktörleri son literatür verileri ışığında tartışılacaktır

Variable prevalence of allergic rhinitis and risk factors affecting the prevalence

Allergic rhinitis is described as a chronic inflammation of the nasal mucosa causing rhinorrhea, sneezing, nasal congestion and itching, often characterized with conjunctival injection and ocular itching. The prevalence of pediatric allergic rhinitis has recently shown a sharp increase throughout the world. However, there are significant differences among the regions, thus indicating to the influence of varying genetic and environmental factors upon the development of allergic rhinitis. This regional difference is mainly related to the ‘western diet’ and ‘western lifestyle’, with its swift changes in environmental and behavioral factors, besides a genetic predisposition. Some main and potential risk factors contributing to the development of allergic rhinitis are still unclear. In this review, we discuss mostly well known and some emerging new risk factors in the light of recent literature.

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