Mehmet Emrah CEYLAN, Gözde CEYLAN, Mustafa TUNÇ

Sublingual Nonsendromik Soliter Nörofibrom Olgu Sunumu

Giriş: Nörofibrom periferik sinir kılıfından köken alan, yavaş büyüyen, benign bir tümördür. Baş ve boyuna yerleşik nörofibromların yüzde 6'sı oral kavitede görülmektedir. Oral kavitede ağız tabanına yerleşik soliter nörofibrom oldukça az görülmektedir. Bu olgu sunumunun amacı bu bölgede nadir görülen bu tümörün tanı ve tedavisine dikkat çekmektir. Olgu Sunumu: Otuz iki yaşında erkek hasta kliniğimize dil altında şişlik şikayetiyle başvurdu. Fizik muayenede ağız tabanında, dili yukarı iten, yaklaşık 3 cm büyüklükte üzeri normal mukoza ile kaplı kitle mevcuttu. Palpasyonda ağız tabanından submandibular bölgeye uzanan hareketli, ağrısız ve sert bir kitle saptandı. Hastaya cerrahi tedavi önerildi. Genel anestezi İmmünhistokimyasal incelemede tümör hücrelerinde S-100 ile pozitif immünreaktivite izlenmesi nedeniyle nörofibrom tanısı kesinleştirildi. Sonuç: Ağız tabanında şişlik şikayeti ile başvuran hastada ön tanılar arasında nörofibromun da yer alması gerektiği, özellikle malign dönüşüm riski taşıyan bu tümörün sendromik hastalıklarla ilişkili olabileceği akılda tutulmalıdır.

A Case Report of Sublingual Nonsyndromic Solitary Neurofibroma

Introduction: Neurofibroma is a slowly growing, benign tumor originating from the peripheral nerve sheath. Neurofibromas observed in oral cavity constitute 6% of those located in head and neck region. Solitary neurofibroma located in the flow of the mouth in oral cavity is observed quite low. The purpose of this case report is to attract attention to the diagnosis and treatment of this rare tumor located in this region. Case Presentation: Thirty-two years old male patient applied to our clinic with swelling under his tongue. In physical examination, a mucosa covered mass was determined that is approximately 3 cm in size and pushing the tongue upwards. In the examination with bimanual palpation, mobile, painless and hard mass was observed to extend from the floor of the mouth to submandibular region. Surgical treatment was recommended to the patient. The excision was performed under general anesthesia and through intraoral route. Immunohistochemical examination confirmed the diagnosis of neurofibroma due to positive immunoreactivity with S-100 in tumorcells. Conclusion: It is important to consider neurofibroma among pre-diagnoses for patients who have applied with swelling on the floor of their mouth, and especially to recognize that this tumor, which has a malignant transformation risk, may be associated with syndromic diseases.

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