Mehmet Emre SİVRİCE, Hasan YASAN, Mustafa TÜZ, ERDOĞAN OKUR, Deniz DİLEK, Vural AKIN

PLATELET-TO-LYMPHOCYTE (PLR) RATIOS IN ADENOIDECTOMY PATIENTS

ObjectiveThe aim of this study is to investigate Platelet-to-lymphocyte(PLR) ratios in children operated for adenoidhypertrophyto determine whether this ratio can be apossible predictive factor in adenoidectomy. We alsoaimed to investigate whether PLR can help indicateongoing systemic inflammation on patients with adenoidhypertrophy.Materials and MethodsOne hundred boys aged 3-11 years, who had undergoneadenoidectomy for adenoid hypertrophybetween 2017 and 2018 at Suleyman Demirel University,Department of Ear Nose and Throat (ENT),were assigned to the study group. The control is 100healthy boys who had been circumcised in the Urologyor Pediatric Surgery Departments. Patients medicalrecords were retrospectively reviewed. The results of preoperative complete blood counts were evaluatedby reviewing the patient files. We calculated thePLR value by dividing platelet count with lymphocytecount.ResultsPLR were 91,68 and 84,15 for control and studygroups respectively and the difference was not statisticallysignificant (Mann-Whitney U test, p = 0.062).The Mann-Whitney U test showed no significant differencebetween study and control groups amongWBC, platelet and lymphocyte counts (p >0.05). PLRof the control group was greater than the study group.ConclusionWe observed platelet and lymphocyte standard deviationsare too high, therefore we beleive that PLR is nota reliable value in adenoidectomy

ADENOİDEKTOMİ YAPILAN HASTALARDA PLATELET-LENFOSİT ORANI

Amaç Bu çalışmada adenoidektomi hastalarında platelet- lenfosit oranının (PLO) prediktif bir faktör olup olmadığının ve adenoid hipertrofisi olan hastalarda platelet-lenfosit oranının sistemik inflamasyonu gösterip göstermediğinin ortaya konulması amaçlandı. Gereç ve Yöntem Çalışma grubuna Süleyman Demirel Üniversitesi Kulak Burun Boğaz Anabilim Dalı’nda (KBB) 2017- 2018 yılları arasında adenoid hipertrofisi tanısı alan 3-11 yaşları arasında toplam 100 erkek hasta dahil edilmiştir. Kontrol grubu, Üroloji ve Çocuk Cerrahisi kliniklerinde sünnet edilen 100 sağlıklı erkekten oluşmaktaydı. Hastaların tıbbi kayıtları retrospektif olarak incelendi. Preoperatif laboratuvar parametreleri hasta dosyaları gözden geçirilerek değerlendirildi. Platelet- lenfosit oranı mutlak platelet sayısının mutlak lenfosit sayısına bölünmesi ile elde edildi. Bulgular Platelet-lenfosit oranı kontrol ve çalışma grupları için sırasıyla 91,68 ve 84,15 idi ve aradaki fark istatistiksel olarak anlamlı değildi (Mann-Whitney U testi, p=0,062). Mann-Whitney U testi ile WBC, platelet ve lenfosit sayıları değerlendirildiğinde çalışma ve kontrol grupları arasında anlamlı bir fark izlenmedi. (p>0,05). Kontrol grubunda platelet-lenfosit oranı, çalışma grubuna göre daha yüksekti. Sonuç Platelet ve lenfosit standart sapmalarının çok yüksek olduğunu gözlemledik, bu nedenle adenoidektomide platelet-lenfosit oranının güvenilir bir değer olmadığı kanaatine varıldı.

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