Defne CEBECİ, Eda EVGEN TÜLÜCEOĞLU, Taner GONCA, Nilüfer ŞAHİN CALAPOĞLU, Önder ÖZTÜRK, Mustafa CALAPOĞLU

AÇLIK SERUM GRELİN DÜZEYLERİ VÜCUT KİTLE İNDEKSİ, KOLESTEROL, TRİGLİSERİT VE C- REAKTİF PROTEİN İLE NEGATİF İLİŞKİLİDİR

Amaç Bu çalışmanın amacı, vücut kitle indeksi (VKİ) kriterlerine göre normal ağırlıktan morbid obeze kadar gruplandırılan erişkin erkek ve kadın kohortunda grelin hormonunun VKİ, serum lipitleri ve C-reaktif protein (CRP) ile ilişkisini değerlendirmektir. Gereç ve Yöntem Isparta Gülkent Devlet Hastanesi Göğüs Hastalıkları Uyku Laboratuvarı ve Süleyman Demirel Üniversitesi Tıp Fakültesi Uyku Hastalıkları Merkezine başvuran 20-59 yaş arası toplam iki yüz altmış erkek (n=151) ve kadın (n=109) çalışmaya dahil edildi. Toplam grelin, CRP, serum lipitleri ve glukoz seviyeleri gece açlığından sonra ölçüldü. Bulgular Grelin düzeyleri obez olgularda istatistiksel olarak anlamlı derecede düşük bulundu (p

FASTING SERUM GHRELIN LEVELS IS NEGATIVELY ASSOCIATED WITH BODY MASS INDEX, CHOLESTEROL, TRIGLYCERIDE AND C-REACTIVE PROTEIN

Objective The aim of this study is to evaluate the relationship of ghrelin hormone with body mass index (BMI) in cohort of adult men and women subsequently categorized from normal weight to morbidly obese based on BMI criteria. The relationship among the total ghrelin, serum lipids and C-reactive protein (CRP) was also evaluated. Materials and Methods Two-hundred sixty men (n=151) and women (n=109) between the ages of 20 and 59 years were recruited from Sleep Disorder Center of Medicine Faculty of Süleyman Demirel University and of Isparta Gülkent State Hospital. Fasting plasma total ghrelin, CRP, serum lipids and glucose levels were measured after overnight fasting. Results Ghrelin levels were found to be statistically significantly lower in obese subjects (P

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