Dopamin ve Ürik Asit Tayini İçin 2-Boyutlu MoSe2 Bazlı Elektrokimyasal Sensör Geliştirilmesi

İki boyutlu (2D) geçiş metal dikalkojenit (TMD) malzemeler sundukları üstün özelliklerden dolayı son yıllarda çok dikkat çekmektedirler. Bu çalışmada, TMD malzemelerin önemli bir üyesi olan molibden diselenür (MoSe2) hidrotermal yöntem ile sentezlenmiş ve çeşitli yöntemlerle yapısal ve morfolojik açıdan incelenmiştir. Analiz sonuçları, MoSe2’ün birkaç katmanlı formda elde edildiğini göstermiştir. MoSe2 daha sonra elektrot modifikasyonunda kullanılmış ve dopamin (DA) ve ürik asitin (UA) eş zamanlı elektrokimyasal tayininde uygulanmıştır. Diferansiyel puls voltametri (DPV) ile gerçekleştirilen tayin çalışmalarından DA için 9.98 – 155 µM arasında ve UA için 19.96 – 310 µM arasında lineer tayin aralıkları belirlenmiştir. Aynı zamanda, geliştirilen sensör askorbik asit (AA) girişiminden etkilenmemekte, kararlı ve tekrar üretilebilir özelliklere sahiptir.

Anahtar Kelimeler:

Geçiş metal dikalkojenit, Molibden diselenür, Elektrokimyasal sensör, Dopamine, Ürik asit, Transition metal dichalcogenide, Molybdenum diselenide, Electrochemical sensor, Uric acid

Development of MoSe2-based Electrochemical Sensor for Detection of Dopamine and Uric Acid

In the recent years, two-dimensional (2D) transition metal dichalcogenide (TMD) materials have attracted much attention due to their unique properties. In this work, molybdenum diselenide (MoSe2), as an important member of TMD materials, was synthesized via hydrothermal method and characterized in terms of structural and morphological analyses. The characterization results exhibited that MoSe2 was formed in few layers. Then, the obtained MoSe2 was used in electrode modification and applied for electrochemical simultaneous determination of dopamine (DA) and uric acid (UA). Differential pulse voltammetry (DPV) studies exhibited linear detection ranges of 9.98 – 155 μM and 19.96 – 310 μM for DA and UA, respectively. Moreover, the developed sensor is not affected by ascorbic acid (AA) interference and showed high stability and reproducibility.

Keywords:

Transition metal dichalcogenide, Molybdenum diselenide, Electrochemical sensor, Uric acid, Dopamine,

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