NURAY YILMAZ ALTINTAŞ, EMRE BALABAN, Mehmet UĞUR, SUBUTAY HAN ALTINTAŞ

Oral bifosfonat tedavisi görmüş olan bir hastanın dental implant destekli protez ile rehabilitasyonu: Olgu sunumu

Bifosfonatlar kemik metabolizmasında osteoklastik inhibitör etkileri nedeniyle birçok kemik ile ilgili hastalıkta yaygın olarak kullanılmaktadır. Son yıllarda intravenöz (İV) ve oral yolla alınan bifosfonatların, ciddi bir yan etkisi olan bifosfonata bağlı çenelerde görülen osteonekroz (BRONJ) hakkında bir çok vaka rapor edilmiştir. BRONJ oluşturma riski yüksek olması nedeniyle İV bifosfonat kullanımı, dental implant uygulamalarında kesin kontraendikasyon olduğu bildirilmiştir. Ancak oral bifosfonat kullanan hastalarda dental implant yapılması ile ilgili öneriler sınırlı verilere dayanmaktadır. Bu olgu raporunda, osteoporoz nedeniyle 3 yıl bifosfonat tedavisi görmüş olan hastanın dental implant destekli protez ile rehabilitasyonu sunulmuştur.

Anahtar Kelimeler:

Bifosfonatlar, dental implant, osteonekroz

The rehabilitation of a patient who received oral bisphosphonate treatment with dental implant supported prosthesis: A case report

Bisphosphonates are widely used in many bone diseases due to their efficient osteoclastic inhibitor effect on bone metabolism. In recent years, numerous cases of bisphosphonate-associated osteonecrosis of the jaw (BRONJ) have been reported as a side effect of both intravenous (IV) and oral therapy regimens. IV administration of bisphosphonates has been considered an absolute contraindication for placement of dental implants due to the increased risk of BRONJ. However, the recommendations were based on limited data about dental implant placement in patients taking oral bisphosphonates. This report documents the rehabilitation of an osteoporotic patient had treated with oral bisphosphonate for 3 years by dental implant supported prosthesis.

Keywords:

Biphosphonates, dental implant, osteonecrosis,

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