Investigation of Antibacterial Activity of Juglone – Poly(ε-caprolactone) - Alumina Composite Films

The aim of this study was to produce Juglone – Poly(ε-caprolactone)(PCL) - Alumina (Al2O3) composite films and determine their antibacterial properties. PCL-Al2O3 composite films containing 1% and 5% juglone were prepared using roll mill method. Juglone – Poly(ε-caprolactone)(PCL) - Alumina (Al2O3) composite films were found to have 100% antibacterial effect on Staphylococcus aureus ATCC 29213 and Escherichia coli ATCC 25922. It is thought that Juglone-PCL-Al2O3 composite films may have potential application in food packaging and personal care products in order to ensure microbial safety and extend shelf life of food and personal care products.

Keywords:

Juglone Poly(ε-caprolactone), Composite, Antibacterial,

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[1] el-R. Kenawy, S.D. Worley, and R. Broughton, “The chemistry and applications of antimicrobial polymers: A state-of-the-art review,” Biomacromolecules, vol. 8, no.5, pp. 1359-1384, 2007.
[2] A.R. Sahahverdi, A. Fakhimi, H.R. Sahahverdi, and S. Minaian, “Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli," Nanomedicine: Nanotechnology, Biology and Medicine, vol. 3, pp. 168-171, 2007.
[3] S.K. Bhullar, D. Rana, B.K. Ozsel, R. Yadav, G. Kaur, M. Chintamaneni, H.S. Buttar, M.B.G. Jun and M. Ramalingam, “A Comparative Study of the Antibacterial Activity of Rosemary Extract Blended with Polymeric Biomaterials”, Journal of Bionanoscience, vol. 10, pp. 326–330, 2016.
[4] A. Solar, M. Colarič, V. Usenik, and F. Stampar, “Seasonal variations of selected flavonoids, phenolic acids and quinones in annual shoots of common walnut (Juglans regia L.),” Plant Science, vol. 170, pp. 453-461, 2006.
[5] T. Zmantar, H. Miladi, B. Kouidhi, Y. Chaabouni, R.B. Slama, A. Bakhrouf, K. Mahdouani and K. Chaieb, “Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity”, Microbial Pathogenesis, vol. 101, pp. 44-49, 2016.
[6] M. Kılınç and H.G. Kutbay, “Bitki ekolojisi,” Palme Publication, pp. 134-135, 2004.
[7] J. Velíšek, J. Davídek, and K. Cejpek, “Biosynthesis of food constituents: Natural pigments. Part 1-a Review,” Czech J. Food Sci., vol. 25, no. 6, pp. 291-315, 2007.
[8] M.P. Strugstad and S. Despotovski., “A Summary of Extraction, Synthesis, Properties, and Potential Uses of Juglone: A Literature Review”, Journal of Ecosystems and Management, vol. 13, no. 3, pp. 1–16, 2012.
[9] M.T. Paulsen and M. Ljungman, “The natural toxin juglone causes degradation of p53 and induces rapid H2AX phosphorylation and cell death in human fibroblasts,” Toxicology and Applied Pharmacology, vol. 209, pp. 1-9, 2005.
[10] M. Saberian, H. Hamzeiy, A. Aghanejad and D. Asgari, “Aptamer-based nanosensors: juglone as an attached-redox molecule for detection of small molecules,” BioImpacts, vol. 1, no. 1, pp. 31-36, 2011.
[11] U. Olgun, K. Tunç and V. Özaslan, “Preparation of antimicrobial polycaprolactone silica composite ﬁlms with nanosilver rods and triclosan using roll-milling method,” Polym. Adv. Technol., vol. 22, pp. 232–236, 2011.
[12] U. Olgun, K. Tunç and A. Hoş, “Preparation and antibacterial properties of nano biocomposite Poly(ε-caprolactone)-SiO2 films with nanosilver,” J Polym Res, vol. 26, no. 24, 2019.
[13] K. Simpson, “Using silver to fight microbial attack,” Plastics Additives & Compounding, pp. 32-35, 2003.
[14] M. Mirjalili and M. Abbasipour, “Comparison between antibacterial activity of some natural dyes and silver nanoparticles,” Journal of Nanostructure in Chemistry, vol. 3, no. 37, pp. 1-3, 2013.
[15] A.C.V. Solano and C.R. Gante “Two Different Processes to Obtain Antimicrobial Packaging Containing Natural Oils”, Food Bioprocess Technol, vol. 5, pp. 2522–2528, 2012.
[16] T. Huang, Y. Qian, J. Wei and C. Zhou, “Polymeric Antimicrobial Food Packaging and Its Applications”, Polymers, vol. 11, no. 560, 2019.
[17] C. Pérez-Pérez, C. Regalado-González, C.A. Rodríguez-Rodríguez, J.R. Barbosa-Rodríguez and F. Villaseñor-Ortega, Incorporation of antimicrobial agents in food packaging films and coatings, Ramón Gerardo Guevara-González and Irineo Torres-Pacheco (eds), Advances in Agricultural and Food Biotechnology, pp. 193-216, Research Signpost, Kerala, India, 2006.
[18] D. Mondal, B. Bhowmick, D. Maity, M.R. Mollick, D. Rana, V. Rangarajan, R. Sen and D. Chattopadhyay, Investigation on Sodium Benzoate Release from Poly(Butylene Adipate-Co-Terephthalate)/Organoclay/Sodium Benzoate Based Nanocomposite Film and Their Antimicrobial Activity, Journal of Food Science, vol. 80, no. 3, 2015.
[19] M. Zhang, X. Gao, H. Zhang, H. Liu, J. Jin, W. Yang and Y. Xie, “Development and antilisterial activity of PE-based biological preservative films incorporating plantaricin BM-1”, FEMS Microbiology Letters, vol. 364, no. 7 2017.
[20] J. Sangsuwan, N. Rattanapanone and I. Pongsirikul, “Development of active chitosan films incorporating potassium sorbate or vanillin to extend the shelf life of butter cake” International Journal of Food Science and Technology, doi:10.1111/ijfs.12631, 2014.
[21] L. A. Cestari, R. C. Gaiotto, J. L. Antigo, M. R. S. Scapim, G. S. Madrona, F. Yamashita, M. S. S. Pozza and I. N. Prado, “Effect of active packaging on low-sodium restructured chicken steaks”, J Food Sci Technol, vol. 52 no. 6, pp. 3376–3382, 2015.
[22] T. Mehdizadeh, H. Tajik, S.M.R. Rohani and A.R. Oromiehie, “Antibacterial, antioxidant and optical properties of edible starch-chitosan composite film containing Thymus kotschyanus essential oil”, Veterinary Research Forum, vol. 3, no. 3, pp. 167-173, 2012.