Gökhan SARGIN, Taşkın ŞENTÜRK, Hakan AKDAM

Periton Diyalizi ve Hemodiyaliz Uygulanan Hastalarda Fibromiyalji Sendromu

Amaç: Fibromiyalji sendromu (FMS) yorgunluk, hafıza problemleri ve yaygın ağrı ile karakterizedir. Sendrom genel popülasyonun yaklaşık % 2-8'inde bulunur. Bununla birlikte, konu ile ilgili belirli popülasyonlardaki bilgiler sınırlıdır. Bizim amacımız, periton diyalizi, hemodiyaliz hastalarında ve kontrol grubunda FMS, klinik ve laboratuvar parametreleri arasındaki ilişkiyi değerlendirmektir.Hastalar ve Yöntemler: Çalışmaya 89 diyaliz hastası ve sağlıklı gönüllü dahil edildi. Kontrol grubu 30 sağlıklı yetişkin (9 kadın, 21 erkek, ortalama yaş 52,9±16,3 yıl), periton diyalizi alan 21 hasta (7 kadın, 19 erkek, ortalama yaş 53±15,9 yıl), ve hemodiyaliz alan 33 hasta (11 kadın, 22 erkek, yaş ortalaması 64,5±7,1 yıl) alındı. Fibromiyalji 1990 American College of Rheumatology (ACR) kriterleri ve 2011 modifiye ACR preliminary tanı kriterlerinin ile konuldu. Cinsiyet, yaş, böbrek fonksiyon testleri, elektrolitler, paratiroid hormon, böbrek yetmezlik etyolojisi ve ne kadar süredir diyaliz yapıldığı kaydedildi.Bulgular: Hemodiyaliz grubuna göre periton diyalizi alan hastalarda fibromiyalji prevalansı daha fazlaydı. Periton diyaliz grubu ile sağlıklı grup arasında istatistiksel olarak anlamlı bir fark yoktu. Ayrıca periton diyalizi grubu ile sağlıklı grup arasında depresyon ve bilişsel işlevler arasında da istatistiksel olarak anlamlı bir farklılık saptanmadı. Ancak, parametreler hemodiyaliz alan hastalarda, periton dializ grubu ve sağlıklı gruba göre daha yüksek olarak bulundu. Böbrek fonksiyon testleri ve elektrolit düzeyleri sağlıklı yetişkin ve diyaliz grupları arasında anlamlı olarak farklıydı (p<0.001).Sonuç: Fibromiyalji prevalansı, periton diyaliz grubu ve sağlıklı grup arasında benzerdi. Bu durum, tedaviye aktif olarak katılma, daha az stres faktörü ve böbrek fonksiyonlarının daha iyi korunması ile ilişkili olabilir. Anahtar Kelimeler: fibromiyalji sendromu, böbrek yetmezliği, periton diyalizi, hemodiyaliz

Anahtar Kelimeler:

fibromiyalji sendromu, böbrek yetmezliği, periton diyalizi

Fibromyalgia Syndrome in Patients Undergoing Peritoneal Dialysis and Hemodialysis

Objectives: Fibromyalgia syndrome (FMS) is characterized by fatigue, memory problems, and widespread pain. The syndrome is present in about %2-8 of the general population. However, knowledge about this topic in specific populations is limited. Our aim was to evaluate FMS in patients undergoing peritoneal dialysis, hemodialysis, and control group, and the association between clinical and laboratory parameters.Patients and Methods: Eighty-nine dialysis patients and healthy volunteers were included in the study. The control group compromised 30 healthy adults (9 females 21 males with mean age of 52,9±16,3 years), 26 patients (7 females 19 males, with mean age of 53±15,9 years) receiving peritoneal dialysis and 33 patients (11 females and 22 males, with mean age of 64,5±7,1 years) receiving hemodialysis were enrolled in this study. Fibromyalgia was diagnosed with the criteria of 1990 American College of Rheumatology (ACR) and 2011 modification of the ACR preliminary diagnostic criteria. Gender, age, renal function tests, electrolytes, parathyroid hormone, renal failure etiology, and how long has it been dialyzed were recorded. Results: The prevalence of fibromyalgia was higher in patients with peritoneal dialysis compared with hemodialysis group. There was no statistically significant between peritoneal dialysis group and healthy group. Also, there was no statistically significant between for depression and cognitive functions between peritoneal dialysis group and healthy group. But, the parameter was found to be high in patients receiving hemodialysis compared with peritoneal and healthy groups. Kidney function tests and electrolyte levels were significantly different between healthy adults and dialysis groups (p <0.001).Conclusion: The prevalence of fibromyalgia was similar between peritoneal dialysis and healthy group. It may be related to actively participate in treatment, fewer stress factors, and better preservation of renal functions.

Keywords:

fibromyalgia syndrome, renal failure, peritoneal dialysis,

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