Pınar DERVİŞOĞLU, Bahri ELMAS, Öner ÖZDEMİR, Mehmet Fatih ORHAN

Pediyatrik COVID-19'da Elektrokardiyografi Değişiklikleri ve Laboratuvar Parametrelerinin Değerlendirilmesi

Amaç: Koronavirüs 19 hastalığının (COVID-19) kardiyak tutulumu elektrokardiyografik (EKG) değişikliklerle yansıtılabilir. Çocuklarda COVID-19 nedeniyle hastane başvurularında meydana gelebilecek EKG değişiklikleri henüz tam olarak değerlendirilmemiştir. Gereç ve Yöntemler: Kanıtlanmış COVID-19 tanısı ile hastaneye başvuran 83 çocuk değerlendirildi. Ayrıntılı klinik muayene, 12 derivasyonlu EKG ve laboratuvar testleri kaydedildi. Tüm laboratuvar değerleri yaşa göre değerlendirildi. Bulgular: P dalga amplitüdü çalışma popülasyonunun% 77.1'inde normal ve% 22.9'unda yüksek bulundu. P dalga amplitüdü normal olan grup ile yüksek grup arasında beyaz kan hücresi (WBC), lenfosit, nötrofil, aspartat aminotransferaz (AST), laktat dehidrojenaz (LDH), D-dimer değerlerinde anlamlı fark vardı. Hastaların % 13.3'ünde birinci derece AV blok varken % 86.7'sinde yoktu. Birinci derece AV blok olan ve olmayan gruplar arasında WBC, lenfosit, D-dimer, AST değerlerinde anlamlı fark vardı. Çalışmamızda 17 olgunun EKG'sinde sağ ventrikül hipertrofisi (RVH) vardı. RVH olan ve olmayan gruplar arasında WBC, lenfosit, D-dimer, LDH, AST değerlerinde anlamlı farklılık vardı. Ayrıca V1R, V6S, V1 R / S oranı ile WBC, lenfosit, D-dimer, kreatinin kinaz (CK), kreatinin kinaz izoform MB (CK-MB), LDH, AST değerleri arasında pozitif korelasyon saptandı. Sonuç: Patolojik EKG bulguları hastalığın seyrinde kullanılan laboratuvar değerleri ile ilişkilendirildi. EKG’nin çocuklarda COVID-19 seyrinde çok önemli bir test olduğunu ve doğru yorumlandığında klinisyenlerin hasta yönetimlerine ciddi katkılar sağlayabileceğini düşünüyoruz.

Anahtar Kelimeler:

Çocuk, COVID-19, elektrokardiyografi

Evaluation of Electrocardiographic Changes and Laboratory Parameters in Pediatric COVID-19

Objective: Cardiac involvement of Coronavirus 19 disease (COVID-19) may be reflected by electrocardiographic (ECG) changes. ECG changes that may occur in hospital admission for COVID-19 in children have not yet been fully evaluated. Materials-Methods: We examined 83 children admitted to our hospital with proven COVID-19. A detailed clinical examination, 12-lead ECG and laboratory tests were recorded. And then all laboratory parameters were evaluated by age. Results: P wave amplitude was normal in 77.1% and high in 22.9% of study population. There was a significant difference in white blood cell (WBC), lymphocyte, neutrophil, aspartate aminotransferase (AST), lactate dehydrogenase (LDH), D-dimer values between the group with P wave amplitude normal and the high group. 13.3% of patients had first degree AV block and 86.7% did not. There was a significant difference between the groups in WBC, lymphocyte, D-dimer, AST values. In our study, there was right ventricular hypertrophy (RVH) in the ECG of 17 cases. There was a significant difference in WBC, lymphocyte, D-dimer, LDH, AST values between groups with and without RVH. In addition, there were positive correlations among V1R, V6S, V1 R / S ratio and WBC, lymphocyte, D-dimer, creatinine kinase (CK), creatinine kinase isoform MB (CK-MB), LDH, AST values. Conclusions: Pathological ECG findings were associated with laboratory values used in the course of the disease. We think that ECG is a test in the course of COVID-19 in children, which may make important contributions to clinicians to manage the patients when interpreted correctly.

Keywords:

Child, COVID-19, electrocardiography,

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