İnsan Anellovirüsleri

Çeşitli biyolojik insan numuneleri üzerinde yüksek verimli sekanslamanın yaygın kullanımı sonucunda bilinen viral tiplerin dağılımı değişmiş ve birçok yeni virüs ortaya çıkmıştır.İnsanları enfekte ettiği bilinen bu virüs ailesi, Alphatorquevirüs genusundan Torque teno virüs, Betatorquevirüs genusundan Torque teno mini virüs ve Gammatorquevirüs genusundan Torque teno midi virüsü içermektedir. Dünya nüfusunda Anellovirüs prevalansı oldukça yüksektir. Bu virüslerin insanlar için patojeniteleri hala net olarak açıklanamamıştır. Yapılan çalışmalarda Anellovirüslerin başta hepatit olmak üzere solunumsal, hematopoetik, bağışıklık sistemi ve kanser gibi birkaç hastalık ile ilişkili olduğu görülmüş olmakla birlikte kesin veriler bulunmamaktadır. Temel viroloji ve immünoloji alanında yapılacak daha kapsamlı ve verimli çalışmalar ile Anellovirüsler hakkında bilgilerimiz artacaktır ve çözüm bekleyen sorularımız cevap bulacaktır.

Human Anelloviruses

The widespread use of high-throughput sequencing on a variety of biological human samples has altered the distribution of known viral types, many new viruses have emerged. Torque teno viruses, closely related to each other within the members of the Anelloviridae family, are recently discovered viruses. It contains Torque teno virus from Alphatorquevirus genus, Torque teno midi virus from Betatorquevirus genus, Torque teno midi virus from Gammatorquevirus genus which are known to infect humans. The prevalence of Anellovirus in the world is very high. The pathogenicity of these viruses to humans is still unclear. Studies have shown that Anelloviruses are associated with several diseases, especially hepatitis, such as respiratory, hematopoietic, immune system, cancer but we still don’t have the exact data. As a result of more comprehensive and efficient work in the field of basic virology and immunology, we will increase our knowledge of Anelloviruses, answer our questions that are pending.

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Sakarya Tıp Dergisi-Cover
  • Başlangıç: 2011
  • Yayıncı: Sakarya Üniversitesi
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