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Evaluation of Cochlear Nerve Diameter with MRI in Patients with Idiopathic Unilateral Sensorineural Hearing Loss

Objective The aim of this study was to evaluate the cochlear nerve diameter in patients with unilateral sensorineural hearing loss and to compare the diameter of the normal sidewith the hearing loss side.Materialsand MethodsA total of 36 patients with idiopathic unilateral sensorineural hearing loss were included in the study. Magnetic resonance imaging (MRI) and pure sound audiogram wereperformed on all the patients. Both cochlear nerve diameters were measured on axial thin-section constructive interference in steady state (CISS) sequences.Results The patients were comprised of 16 males and 20 females with a mean age of 52.3±13.7 years. Hearing loss was in the right ear in 11 patients, and in the left ear in 25. Theaverage cochlear nerve diameter on the side with hearing loss was 0.13 cm while it was 0.19 cm on the normal side. There was a statistically significant difference betweenthe two sides (p < 0.001).Conclusion In patients with unilateral sensorineural hearing loss, MRI allows the assessment of the cochlear nerve with anatomic detail, and enables the exclusion of possible organicpathologies. Demonstration of decreased cochlear nerve diameter in idiopathic sensorineural hearing loss will contribute to elucidating the etiology of this disease in thefuture.

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1. Schuknecht HF, Gacek MR, Cochlear pathology in presbycusis. Ann Otolaryngol. 1993;102: 1-16.
2. Westerhof JP, Rademaker J, Weber BP, Becker H, Congenital malformations of the inner ear and the vestibulocochlear nerve in children with sensorineural hearing loss: evaluation with CT and MRI. J Comput Assist Tomogr. 2001; 25: 719-726.
3. Glastonbury CM, Davidson HC, Harnsberger HR, Butler J, Kertesz TR, Shelton C, Imaging findings of cochlear nerve deficiency. AJNR Am J Neuroradiol. . 2002; 23: 635-643.
4. Furuta S, Ogura M, Higano S, Takahashi S, Kawase T, Reduced size of the cochlear branch of the vestibulocochlear nerve in a child with sensorineural hearing loss. AJNR Am J Neuroradiol. 2000; 21: 328-330.
5. Lou J, Gong W-X, Wang G-B, Cochlear nerve diameters on multipoint measurements and effects of aging in normal-hearing children using 3.0-T magnetic resonance imaging. Int J Pediatr Otorhinolaryngol. 2015; 79: 1077-1080.
6. Kang WS, Hyun SM, Lim HK, Shim BS, Cho JH, Lee KS, Normative diameters and eff ects of aging on the cochlear and facial nerves in normal‐hearing Korean ears using 3.0‐tesla magnetic resonance imaging. Laryngoscope. 2012; 122: 1109-1114.
7. Nakamichi R, Yamazaki M, Ikeda M, Isoda H, Kawai H, Sone M, Nakashima T, Naganawa S, Establishing normal diameter range of the cochlear and facial nerves with 3D-CISS at 3T. Magn Reson Med Sci. 2013; 12: 241-7.
8. Russo EE, Manolidis S, Morriss MC, Cochlear nerve size evaluation in children with sensorineural hearing loss by high-resolution magnetic resonance imaging. Am J Otolaryngol. 2006; 27: 166-72.
9. Nakano A, Arimoto Y, Matsunaga T, Cochlear nerve deficiency and associated clinical features in patients with bilateral and unilateral hearing loss. Otol Neurotol. 2013; 34: 554-8.
10. Sildiroglu O, Cincik H, Sonmez G, Ozturk E, Mutlu H, Gocgeldi E, Tunca Keskin A, Basekim C, Kizilkaya E, Evaluation of cochlear nerve size by magnetic resonance imaging in elderly patients with sensorineural hearing loss. Radiol Med. 2010; 115: 483-7.
11. Naguib NNN, Hey C, Shaaban MS, Elabd AM, Hassan HHM, Gruber-Rouh T, Kaltenbach B, Harth M, Ackermann H, Stover T, Vogl TJ, Nour-Eldin NA, Assessment of the cochlear nerve to facial nerve size ratio using MR multiplanar reconstruction of the internal auditory canal in patients presenting with acquired long-standing hearing loss. Br J Radiol. 2017;90: 20160870.
12. Golub JS, Lin FR, Lustig LR, Lalwani AK, Prevalence of adult unilateral hearing loss and hearing aid use in the United States. Laryngoscope. 2018; 128: 1681-1686.
13. Lee JW, Bance ML, Hearing loss. Pract Neurol. 2018.
14. Gonçalves FG, do Amaral LLF, Constructive interference in steady state imaging in the central nervous system. Eur Neurol Rev. 2011; 6: 138-42.
15. Liang C, Zhang B, Wu L, Du Y, Wang X, Liu C, Yu F, Th e superiority of 3D-CISS sequence in displaying the cisternal segment of facial, vestibulocochlear nerves and their abnormal changes. Eur J Radiol. 2010; 74: 437-40.