ANTRENMANLI ERKEK BİREYLERDE ANAEROBİK EŞİKTE YAPILAN EGZERSİZİN NESFATİN-1 HORMONU ÜZERİNE OLANETKİLERİNİN BELİRLENMESİ

Anaerobik eşikte yapılan egzersizin nesfatin-1 seviyeleri üzerine etkileri antrenmanlı erkek deneklerde araştırıldı. Toplam 30 erkek denek sabah saatlerinde 30 dakikalık aerobik koşma egzersizi gerçekleştirdi. Venöz kan örnekleri istirahat ve test sonunda alındı. Nesfatin-1 seviyesi ELISA metodu ile belirlendi. Nesfatin-1 değerleri istirahatte 102.8±5.1 ng/ml olarak tespit edilmiş ve test sonunda 109.6±6.2 ng/ml seviyesine yükselmiştir. Fakat bu yükselme istatistiksel olarak belirgin değildir (P=0.3). Nesfatin-1 seviyesi vücut ağırlığına standardize edildiğinde 1.695±0.09 ng/ml/kg olarak bulunmuştur. Vücut ağırlığının nesfatin-1 seviyelerine oranı ile egzersiz sırasında nesfatin-1 seviyesi değişimi arasında bir korelasyon bulundu: R=0.50858 (p=0.004). Bu çalışmada nesfatin-1’in egzersiz kaynaklı bir hormon olmadığını fakat bireyden bireye artma veya azalma değişiklik gösterdiğini elde ettik. Bu nedenle değişik fitnes seviyesindeki deneklerde ileri çalışmalara ihtiyaç duyulmaktadır.

Anahtar Kelimeler:

Egzersiz, Anaerobik eşik, Nesfatin1, Enerji, Fitnes

Determination of Effects of Exercise at Anaerobic Threshold on Nesfatin-1 Hormone in Trained Male Subjects

The effects of exercise at the anaerobic threshold on nesfatin-1 levels have been investigated in trained male subjects. A total of 30 males performed an aerobic running exercise for 30 min in mornings. Venous blood samples were taken at rest and at the end of the test. ELISA method was used to analyse nesfatin-1 levels. Nesfatin-1 levels were found to be 102.8±5.1 ng/ml at rest and it increased to 109.6±6.2 ng/ml at the end of the test. However, this increase was not statistically significant (P=0.3). The nesfatin-1 level was found to be 1.695±0.09 ng/ml/kg when standardised to body weight. There was a correlation between body weight to nesfatin-1 levels and change of nesfatin-1 levels during exercise: R=0.50858 (p=0.004). We showed that nesfatin-1 is not exercise induced hormone but it may vary among the subjects either increasing or decreasing. Thus further studies should be performed in subjects with carying fitness status.

Keywords:

Exercise, Anaerobic threshold, Nesfatin-1, Energy, Fitness,

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