Ozlem GURSOY, Ceren YILDIZ EREN, Hulusi Göktuğ GÜRER

Ovaryan endometrozis ve D vitamini düzeyi arasındaki ilişki

OVARYAN ENDOMETROZİSDE D VİTAMİNİ DÜZEYLERİ ÖZET Giriş ve Amaç: D vitamininin endometriozis patogenezindeki potansiyel rolü araştırmacılar tarafından üzerinde çalışılan bir konudur. Bu çalışma, endometriozisin çeşitli özellikleri ile D vitamini düzeyleri arasındaki ilişkiyi araştırmak amacıyla yapılmıştır. Gereç Yöntemler: Katılımcıların sosyodemografik özellikleri olarak yaş, parite ve sigara içme değişkenleri incelendi. Çalışmamızda incelenen diğer değişkenler evre, anti-Müllerian hormon ve D vitamini düzeyleri, endometriozisin, sağda veya solda, görüldüğü taraf, endometriozisin yaygınlığı ve infertilite durumudur. Tanımlayıcı istatistiksel yöntemler, korelasyon analizi, regresyon analizi, bağımsız örnekler t testi ve tek yönlü varyans analizi kullanılmıştır. Bulgular: Korelasyon analizine göre kandaki D vitamini düzeyi ile evre arasında istatistiksel olarak anlamlı, orta düzeyde bir ilişki vardır. Regresyon modeline göre kandaki D vitamininin evre üzerinde olumsuz ve anlamlı bir etkisi vardır. Bu bulgulara göre D vitamini seviyesindeki düşüşün hastanın evre durumunu yükselteceği söylenebilir. Sonuç: Araştırmanın birincil konusu olan D vitamini ile endometriozis arasındaki ilişki üç farklı istatistiksel yöntemle araştırıldı.

Anahtar Kelimeler:

Endometriozis, D Vitamini, Anti-Müllerian Hormon, Parite, Sigara, İnfertilite.

The relationship between ovarian endometrosis and vitamin D level

ABSTRACT Introduction & Aim: The potential role of vitamin D in the pathogenesis of endometriosis is a subject that has been studied by researchers. This study was carried out to investigate the correlation between various features of endometriosis and vitamin D levels. Material Methods: Age, parity and smoking variables of the participants were examined as socio-demographic characteristics. Other variables examined in our study are stage, anti-Müllerian hormone and vitamin D levels, the side where endometriosis is seen, either right or left, the extent of endometriosis and infertility status. Descriptive statistical methods, correlation analysis, regression analysis, independent samples t-test and one-way analysis of variance were used. Results: According to the correlation analysis, there is a statistically significant, moderate relationship between the level of vitamin D in the blood and the stage. According to the regression model, vitamin D in the blood has a negative and significant effect on the stage. According to these findings, it can be said that the decrease in vitamin D level will increase the stage status of the patient. Conclusions: The correlation between vitamin D and endometriosis, which is the primary subject of the research, was investigated with three different statistical methods.

Keywords:

Endometriosis, Vitamin D, Anti-Mullerian Hormone, Parity, Smoking, Infertility.,

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