Çocuklarda Ayna Hayali Hareketler; Tek Merkez Deneyimi
Ayna hayali hareketler(MMs), kontralateral homolog kaslarda istemli aktiviteye eşlik eden istemsiz hareketlerdir. Ayna hayali hareketleri, bir dizi patolojik durumla ilişkilendirilmiştir, ayrıca çocuklukta fizyolojik olarak, on yaşından önce ortaya çıkabilir. Bu çalışmada, ayna hayali hareket saptanan 27 hastanın etiyolojik ve klinik özelliklerini retrospektif olarak değerlendirdik.Hastaların klinik, demografik ve laboratuvar verileri retrospektif olarak değerlendirildi. Ayna hayali hareketlerin değerlendirmesi için Rasmussen ölçeği kullanıldı.İki hasta fizyolojik MMs olarak değerlendirildi. On bir hasta unilateral spastik serebral palsi ve 14 hasta ise hemiplejik olmayan çocuklardı.Bu çalışma, çocuklarda en büyük MMs vaka serilerinden biridir. Bu çalışmada ayna hayali hareketler ile birlikteliği ilk defa gösterilen hastalıklar da tanımlanmıştır. En azından risk gruplarında, ayna hayali hareketlerin saptanması için yapılacak bir değerlendirmenin, nörolojik muayenenin bir parçası olabileceğine inanıyoruz.
Mirror Movement in Children; A Single Center Experience
Mirror movements (MMs) are involuntary movements accompanying voluntary activity in contralateral homologous muscle. Mirror movements have been associated with a number of pathologic conditions, also it might occur physiologically in childhood and subside before the age of ten. In this study, we retrospectively evaluate etiologic and clinical features of the 27 patients with MMs.Clinical, demographic and laboratory data of the patients were obtained by evaluating medical records retrospectively. The Rasmussen scale was used to measure the severity of the MMs. Two children were diagnosed as physiologic MMs. Eleven children were unilateral spastic cerebral palsy and 14 patients were non-hemiplegic children. This study is one of the largest case series of MMs in children. We identified new disorders with MMs by using the Rasmussen scale. We suggest that an evaluation for MMs may be a part of neurologic examinations, at least in risk groups
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- 1. Cincotta M, Lori S, Gangemi PF, Barontini F, et al. Hand Motor Cortex Activation in a Patient with Congenital Mirror Movements: a Study of the Silent Period Following Focal Transcranial Magnetic Stimulation. Electroencephalogr Clin Neurophysiol 1996;101(3):240-6.
- 2. Verstynen T, Spencer R, Stinear CM, Konkle T, et al. Ipsilateral Corticospinal Projections do not Predict Congenital Mirror Movements: a Case Report. Neuropsychologia. 2007;45(4):844-52
- 3. Adler C, Berweck S, Lidzba K, Becher T, et al. Mirror Movements in Unilateral Spastic Cerebral Palsy: Specific Negative Impact on Bimanual Activities of Daily Living. Eur J Paediatr Neurol. 2015;19(5):504-9.
- 4. Cincotta M, Ziemann U. Neurophysiology of Unimanual Motor Control and Mirror Movements. Clin Neurophysiol. 2008;119(4):744-62
- 5. Cincotta M, Borgheresi A, Balestrieri F, Giovannelli F, et al. Involvement of the Human Dorsal Premotor Cortex in Unimanual Motor Control: an Interference Approach Using Transcranial Magnetic Stimulation. Neuroscience Letters. 2004;367(2):189-93
- 6. Gazzaniga MS. Cerebral Specialization and Interhemispheric Communication. Does the Corpus Callosum Enable the Human Condition?. Brain. 2000;123(7):1293-326.
- 7. Müller K, Kass-Iliyya F, Reitz M. Ontogeny of Ipsilateral Corticospinal Projections: A Developmental Study with Transcranial Magnetic Stimulation. Ann Neurol. 1997;42(5):705-11.
- 8. Rasmussen P. Persistent Mirror Movements: A Clinical Study of 17 Children, Adolescents and Young Adults. Dev Med Child Neurol. 1993;35(8):699-707
- 9. Rizzolatti G, Luppino G. The Cortical Motor System. Neuron. 2001;31(6):889-901
- 10. Cincotta M, Borgheresi A, Boffi P, Vigliano P, et al. Bilateral Motor Cortex Output with Intended Unimanual Contraction in Congenital Mirror Movements. Neurology. 2002;58(8):1290-3.
- 11. Galléa C, Popa T, Billot S, Méneret A, et al. Congenital Mirror Movements: A Clue to Understanding Bimanual Motor Control. J Neurol. 2011;258(11):1911-9
- 12. Chen LC, Liu MY, Hsiao YC, Choong WK, et al. Decoding the Disease-associated Proteins Encoded in the Human Chromosome 4. J Proteome Res. 2013;12(1):33-44.
- 13. Depienne C, Cincotta M, Billot S, Bouteiller D, et al. A Novel DCC Mutation and Genetic Heterogeneity in Congenital Mirror Movements. Neurology. 2011;76(3):260-4.
- 14. Erol FS, Topsakal C, Ozveren MF, Akdemir I, et al. Meningocele with Cervical Dermoid Sinus Tract Presenting with Congenital Mirror Movement and Recurrent Meningitis. Yonsei Med J. 2004;45(3):568-72
- 15. Mahirogullari M, Ozkan H, Yildirim N, Cilli F, et al. Klippel-Feil Syndrome and Associated Congenital Abnormalities: Evaluation of 23 Cases. Acta Orthop Traumatol Turc. 2006;40(3):234-9.
- 16. Reitz M, Müller K. Differences Between Congenital Mirror Movements and Associated Movements in Normal Children: A Neurophysiological Case Study. Neurosci Lett. 1998;256(2):69-72
- 17. Gunderson CH, Solitare GB. Mirror Movements in Patients with the Klippel-Feil Syndrome. Neuropathologic Observations. Arch Neurol. 1968;18(6):675-9.
- 18. Schott GD, Wyke MA. Congenital Mirror Movements. J Neurol Neurosurg Psychiatr. 1981;44(7):586-99
- 19. Nadkarni NA, Deshmukh SS. Mirror Movements. Ann Indian Acad Neurol. 2012;15(1):13-4
- 20. Orth M, Münchau A. Transcranial Magnetic Stimulation Studies of Sensorimotor Networks in Tourette Syndrome. Behav Neurol. 2013;27(1):57-64