Hayriye ŞAHİNLİ, Mustafa Gökhan VURAL, Göksal KESKİN

Behçet hastalarında pulmoner arter sertliğinin değerlendirilmesi

Amaç: Behçet hastalığı her boyda arter ve venleri etkileyen sistemik bir vaskülittir. Behçet hastalığında, aort ve pulmoner arter anevrizması en önemli mortalite nedenlerindendir. Anevrizmanın histopatolojisinde, damar duvarında tam kat düzensiz fibröz kalınlaşma rol oynamaktadır. Büyük damarlardaki sertliğin artmasıyla kardiovasküler mortalite ve morbiditenin arttığı bulunmuştur. Behçet hastalarında pulmoner arter elastisite özelliklerini invaziv olmayan yöntemlerden biri olan ekokardiografi (EKO) ile değerlendirmeyi amaçladık. Gereç ve Yöntemler: Çalışmaya 27 Behçet hastası (18 kadın, 9 erkek) ve 21 sağlıklı kontrol grubu ( 9 kadın, 12 erkek) alındı. Pulmoner arter, ekokardiografi ile değerlendirildi. Pulmoner elastisite parametreleri olarak pulmoner strain, beta indeksi ve distensibilite alındı. Bulgular: Çalışmaya 27 Behçet olgusu ile 21 sağlıklı kontrol grubu alındı. Kontrol grubuna göre, Behçet hastalığı grubunda pulmoner arter strain ve pulmoner arter distensibilite değeri anlamlı olarak daha düşük bulundu (p<0,001, p<0,001). Pulmoner arter beta indeksi ise anlamlı olarak daha yüksek bulundu (p=0,022) . Sonuç: Behçetli hasta grubunda pulmoner sertliğin, sağlıklı kontrol grubuna göre anlamlı olarak arttığı sonucuna varılmıştır. Erken dönemde, pulmoner arter anevrizmasının tesbitinde, pulmoner arter sertliğinin ekokardiografi ile değerlendirilmesi kullanılabilir bir yöntemdir.

Anahtar Kelimeler:

Behçet hastalığı, pulmoner arter anevrizması, pulmoner arter sertliği

Evaluation of pulmonary artery stiffness patients with Behcet's disease

Aim: Behçet's disease is a systemic vasculitis affecting arteries and veins in every dimension. Aortic and pulmonary artery aneurysms are the most important causes of mortality in Behçet's disease. In the histopathology of the aneurysm, full-thickness irregular fibrous thickening plays a role in the vessel wall. Cardiovascular mortality and morbidity were found to increase with increasing stiffness in the large vessels.We aimed to evaluate the pulmonary artery elasticity in patients with BD with Echocardiography (ECO) which is one of the non-invasive methods. Material and Methods: Twenty seven (18 female, 9 male) Behcet’ patients and twenty one healthy controls (9 female, 12 male) are included to the study. Pulmonary artery is evaluated with ECO. Pulmonary strain, beta index, distensibility are used as pulmonary elasticity parameters.Results: Twenty seven Behcet’ patients and twenty one healthy controls are included to the study. Pulmonary artery strain and pulmonary artery distensibility values of the Behcet’s group were observed to be significantly lower than the control group (p<0,001, p<0,001); where as pulmonary artery beta index was significantly higher ( p=0,022). Conclusion: Pulmonary stiffness is significantly increased in patients with Behcet’s disease compaired to healty control group.for identification of pulmonary artery aneurizm in an early echocardiographic examination of pulmoner artery stiffness can be used.

Keywords:

Behcet's disease, pulmonary artery aneurysm, pulmoner artery stiffness,

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