Covid-19 Pandemisi ve Kronik Böbrek Hastalarına Etkisi / Covid-19 of Pandemic and Impact on Patients with Chronic Kidney Disease

Tek zincirli, pozitif polariteli, zayıf bir RNA virüsü olan “SevereAcute Respiratory Syndrome Coronavirüs-2 (SARS-CoV2)”kısa sürede tüm dünyaya yayılmıştır. Covid-19 etkeni olanSARS-CoV-2 virüsünün kuluçka süresinin mevcut verilere göre2-14 gün arasında olduğu ve yaygın olarak halsizlik, ateş, boğazağrısı, kuru öksürük, nefes darlığı, eklem ağrısı, koku kaybı gibisemptomlar ile belirti vermektedir. Covid-19 enfeksiyonunun,hastalarda çoğunlukla akut böbrek hasarına yol açması ve kronikböbrek hastalarının çoğunda birden fazla komorbid hastalıkvarlığının mevcut olması kronik böbrek hastalarında mortaliteve morbidite oranlarının artmasına neden olmaktadır. Covid-19tanısıyla hastaneye yatan hastalarda böbrek fonksiyonlarıincelendiğinde, hastaların %59'u proteinüri, %44'ü hematüribulunduğu, %31'inin kan üre nitrojenin (BUN) ve %22'sininserum kreatinin düzeyinin arttığı ve böbrek fonksiyonbozukluğu belirtileri bulunduğu görülmüştür. Üremi nedeniylebağışıklık sistemleri baskılanmış olan hemodiyaliz, peritondiyaliz ve böbrek transplantasyonu yapılan hastalar, Covid-19enfeksiyonu için yüksek riskli grup olarak belirtilmektedir. Buderlemede, Covid-19 enfeksiyonunun böbrek fonksiyonlarını vekronik böbrek hastalığı tedavisi gören hastaları nasıl etkilediğineyer verilmiştir.

Covid-19 of Pandemic and Impact on Patients with Chronic Kidney Disease

“Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV2)”, a single-stranded, positive polarity, weak RNA virus, has spread all over the world in a short time. The incubation period of the SARS-CoV-2 virus, which is the causative agent of Covid-19, is between 2-14 days according to the available data and it commonly presents with symptoms such as weakness, fever, sore throat, dry cough, shortness of breath, joint pain, loss of smell. The fact that Covid-19 infection mostly causes acute kidney injury in patients and the presence of more than one comorbid disease in most chronic kidney patients causes an increase in mortality and morbidity rates in chronic kidney patients. When kidney functions were examined in patients hospitalized with the diagnosis of Covid-19, 59% of the patients had proteinuria, 44% had hematuria, 31% had blood urea nitrogen (BUN) and 22% had increased serum creatinine levels and signs of kidney dysfunction. Patients undergoing hemodialysis, peritoneal dialysis, and kidney transplantation, whose immune systems are suppressed due to uremia, are indicated as a high-risk group for Covid-19 infection. In this article, it has been discussed how Covid-19 infection affects the function of the kidney and patients treated for chronic kidney disease.

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