Kronik Böbrek Yetmezliği Hastalarında Renal ve Tiroid Fonksiyon Testlerinin Değerlendirilmesi

Böbreğin, normalde tiroid hormonlarının metabolizmasında, parçalanmasında ve atılmasında önemli bir rol oynadığı bilinmektedir. Bu durumda böbrek fonksiyonunda meydana gelen bir bozulmanın, tiroid fizyolojisini de etkilemesi beklenmektedir. Çalışmamızda; hemodiyaliz tedavisi gören kronik böbrek yetmezliği olan hastalarda, tek bir hemodiyaliz seansının tiroid fonksiyonuna etkisini araştırmayı ve hemodiyaliz hastalarında tiroid fonksiyon testleri ve bazı biyokimyasal parametreleri sağlıklı gruplarla karşılaştırmayı amaçladık. 29 hastadan (ortalama yaş: 46.17 ± 14.93) diyaliz öncesi ve sonrasında aldığımız kan örnekleri ile kontrol grubu olan 28 sağlıklı katılımcıdan (ortalama yaş: 40.79 ± 14.42) aldığımız kan örnekleri otoanalizör ile analiz edildikten sonra istatistiksel olarak değerlendirildi. Diyaliz öncesi ve sonrası örnekler karşılaştırıldığında TT4, FT3 ve FT4 değerleri istatistiki olarak anlamlı bulundu (sırasıyla p 0.1), aynı grubun TT3 (p

Evaluation of Renal and Thyroid Function Tests in Chronic Renal Failure Patients

It is known that the kidney normally plays an important role in the metabolism, degradation and excretion of several thyroid hormones. Accordingly, deterioration in renal function is expected to lead to disturbing thyroid physiology. In the study, we aimed to investigate the effect of a single hemodialysis session on thyroid function in patients with chronic renal failure that have hemodialysis treatment, and also to compare thyroid function tests and some biochemical parameters in hemodialysis patients with healthy groups. We collected blood samples which were drawn pre- and after-dialysis sessions from 29 patients (mean age: 46.17 ± 14.93) and 28 healthy participants (mean age: 40.79 ± 14.42) as control group, and analysed using an autoanalyzer followed by statistical analysis. TT4, FT3 and FT4 values were found statistically significant (p 0.1). In addition, statistical results proved that creatinine - FT4 values (p

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