Distribution and Characterization of Aeroallergens in the Etiology of Allergic Rhinitis Patients in İstanbul Kartal Region

Aim: Allergic rhinitis (AR) is a common disease and the first step in its treatment is to determine the allergen responsible for its etiology and totake preventive measures. The aim of this study was to determine the distribution of aeroallergens in AR patients in İstanbul Kartal region and toinvestigate other factors affecting the severity of AR.Materials and Methods: The study was performed in a tertiary hospital on the Anatolian side of İstanbul among patients who were admitted tothe allergy and clinical immunology outpatient clinic and diagnosed with AR. Data of patients were obtained from medical records retrospectively.Age, gender, concomitant atopic disease, family transition history, serum total IgE and serum eosinophil (Eo) levels were evaluated. Skin prick testswere performed with 25 allergens.Results: One hundred and sixty patients were included in our study. Ninety-six (65.8%) of the patients were female and the median age of the studypopulation was 31 (18-75) years. Distribution of aeroallergens according to skin test results was as follows; D. pteronyssinus (78.1%), D. farinae(75.2%), Tyrophagus putrescentlae (59.6%), Acurus siro (57.5%), Lepidoglyphus destructor (40.4%), cereals mix (37.7%), and cat hair (33.6%). It wasfound that there was a significant increase in total IgE levels (p

İstanbul Kartal Bölgesi Alerjik Rinit Hastalarının Etiyolojisindeki Aeroalerjenlerin Dağılımı ve Karakterizasyonu

Amaç: Alerjik rinit (AR) yaygın görülen bir hastalıktır ve tedavisinde ilk basamak, etiyolojisindeki sorumlu alerjeni saptayıp koruyucu önlemleri almaktır. Çalışmamızın amacı, İstanbul Kartal yerleşkesinde yaşayan AR hastalarının etiyolojisinde rol alan aeroalerjenlerin dağılımını tespit etmek ve AR şiddetini etkileyen faktörleri araştırmaktır. Gereç ve Yöntem: Çalışma, İstanbul Anadolu yakasında bulunan üçüncü basamak bir hastanede gerçekleştirildi. Alerji ve klinik immünoloji polikliniğine rinit şikayeti ile başvurup AR tanısı konulan hastalar çalışmaya dahil edildi ve dosyaları geriye dönük olarak incelendi. Hastaların yaş, cinsiyet, eşlik eden diğer atopik hastalıkları, aile geçiş öyküsü, serum total IgE ve serum eozinofil (Eo) seviyeleri değerlendirildi. Deri prick testleri 25 adet alerjen ile yapıldı. Bulgular: Çalışmamıza 146 hasta dahil edildi. Hastaların 96’sı (%65,8) kadındı. Medyan yaş 31 (18-75) yıl olarak saptandı. Deri prick test sonuçlarına göre aeroalerjenlerin dağılımı sırasıyla; D. pteronyssinus (%78,1), D. farinae (%75,2), Tyrophagus putrescentlae (%59,6), Acurus siro (%57,5), Lepidoglyphus destructor (%40,4), cereals mix (%37,7), kedi tüyü (%33,6) şeklindeydi. Hastaların serum Eo seviyesindeki artışa paralel olarak total IgE düzeylerinde de anlamlı artış olduğu (p

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