Çanakkale İlinde Aterosklerotik Kardiyovasküler Hastalıkların İçme Suyu Sertlik Seviyesi ile İlişkisi

Amaç: Kardiyovasküler hastalıklar (KVH) ölüm sebepleri içerisindeki liderliğini halen korumaktadır. Risk faktörleri ve hastalık ilişkisi ile ilgili pek çok çalışma yapılmış ve ispatlanan öneriler güncel kılavuzlara girmiştir. Fakat su sertliği ve KVH ilişkisi ile ilgili literatürde karşıt yorumların olduğu ve halen kesin kanaatlere varılamadığı görülmektedir. Çanakkale şehir merkezinde içme suyu ihtiyacı sertlik derecesi farklı iki ayrı kaynaktan karşılanmaktadır. Bu durum su sertlik seviyesi ve KVH ilişkisinin daha iyi anlaşılmasına yardımcı olabilir. Bu amaçla çalışma planlanmıştır. Gereç ve Yöntem: 2015-2020 yılları arasında Çanakkale Onsekiz Mart Üniversitesi Eğitim ve Uygulama Hastanesi’ne başvurmuş ateroskleroz ile ilişkili tanısı olan (koroner arter, karotis arter ve periferik arter hastalığı) Çanakkale il merkezine kayıtlı olgular retrospektif olarak tespit edilerek aterosklerotik (AS) grup oluşturuldu. Bu gruba karşılık gelecek şekilde olguların yaş, cinsiyet, arteriyel hipertansiyon (HT), diabetes mellitus (DM), dislipidemi (DL) mevcut olması durumuna göre, “propencity score matching” gözetilerek non-AS grup oluşturuldu. Yerel yönetimlerden elde edilen il merkezi içme suyu analizlerinden pH, sertlik, kalsiyum, magnezyumun son beş yıllık değerleri tespit edilip adres ile ilişkilendirildi. Bu bilgiler kullanılarak farklı sertlikte su tüketen olgular tespit edildi. İstatistiki olarak iki grup arasındaki su sertlik değeri açısından anlamlılık değerlendirildi. Bulgular: Gruplar arasında yaş, cinsiyet, HT, DM, DL’de anlamlı farklılık yoktu (p>0,05), non-AS grubunda çok yüksek sertlikte su tüketiminin anlamlı seviyede yüksek olduğu tespit edildi (p

The Relationship Between Aterosclerotic Cardiovascular Diseases and Drinking Water Hardness Level in Çanakkale Province

Aim: Cardiovascular diseases (CVH) still maintain their leadership among causes of death. Many studies have been carried out on risk factors and the relationship of disease and their proven recommendations have entered current guidelines. However, it is seen that there are opposing interpretations in the literature regarding the relationship between water hardness and CVH and definite conclusions are still not reached. In Çanakkale province center, drinking water needs are met from two different sources with different hardness degrees. This may help to better understand the relationship between water hardness level and CVH. The study was designed for this purpose. Materials and Methods: Patients with a diagnosis of atherosclerosis (coronary artery, carotid artery and peripheral artery disease), who applied to Çanakkale Onsekiz Mart University Training and Practice Hospital between 2015 and 2020, were retrospectively identified, and atherosclerotic group was formed. Corresponding to this group, a non-atherosclerotic (non-AS) group was formed by observing “propensity score matching” according to age, gender, arterial hypertension (HT), diabetes mellitus (DM), and presence of dyslipidemia (DL). The pH, hardness, calcium, magnesium values of the last five years were determined from the city center drinking water analyses taken from local governments and were associated with the address. Using this information, cases consuming water of different hardness were determined. Statistically, the significance of the water hardness values between the two groups was evaluated. Results: There was no significant difference in age, gender, arterial HT, DM, DL between the groups (p>0.05), and very high hardness water consumption was found significantly higher in the non-AS group (p

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