Selahattin ÇALIŞKAN, Mustafa SUNGUR, Emrah ÖZSOY, Orhan KOCA

The renal neoplastic lesions in non-functioning kidney patients who underwent simple nephrectomy

The simple nephrectomy is usually performed in daily urology practice for the non-functioning kidney. The aim of this study is to determine the incidental malignancy rate of the patients who underwent nephrectomy procedure. In total, 258 patients were included in the study. The patients who underwent simple nephrectomy and diagnosed as renal tumor between January 2003 and March 2016 for the non-functioning kidney at our department were recorded. There were 258 patients in this study. Of these patients;123 were male and 134 were female patients. The mean age of the patients’ was 52.33+17.63 years. The presence of stone formation was detected in 92 patients (35.65%). The renal malignancy was reported in 9 patients.Among the patients with malignancy; 2 patients were female and 7 patients were male. The mean age of the patients was 54.77+8.81 years. The pathological examination revealed that 6 patients were transitional cell carcinoma (TCC) of the renal pelvis, 2 patients were renal cell carcinoma, one patient was cystic nephroma. Interestingly, nephrolithiasis was detected only in one patient. The prevalence of all malignancy and the malignant tumor was 3.48% and 3.10% in this study. The final pathology showed that there is a risk of malignancy fort he patients with the non-functioning kidney. The clinicians should be aware that the patient may be diagnosed as renal tumor after pathological examination.

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Abdulkareem AS, Hassawi BA, Ahmed Z. Nephrectomy, A clinicopathological study. J Am Sci.2015;11(8):97-101.

Zengin K, Tanık S, Sener NC, et al. Incidence of renal carcinoma in non-functioning kidney due to renal pelvic stone disease. Mol Clin Oncol.2015;3(4):941-3.

Desai FS, Nongthomban J, Singh LS. Retrospective evaluation of risk factors and immunohistochemical findings for pre-neoplastic and neoplastic Lesions of upper urinary tract in patients with chronic nephrolithiasis. Asian Pac J Cancer Prev. 2015;16(18):8293-8.

Raghavendran M, Rastogi A, Dubey D, et al. Stone associated renal pelvic malignancies. Indian J Cancer. 2003;40(3):108-12.

Mindrup SR, Pierre JS, Dahmoush L, et al. The prevalence of renal cell carcinoma diagnosed at autopsy. BJU Int.2005;95(1):31-3.

Dell’Atti L. An unusual presentation of cystic nephroma in an adult man. Rare Tumors. 2015;7(2):81-3.

Edmunds W. Cystic adenoma of the kidney. Trans Pathol Soc London. 1892;43:89-90.