Stress and recurrent aphthous stomatitis

Recurrent aphthous stomatitis (RAS) is a commonly-encountered oral lesion. The aim of this study was to identify the levels of stress, anxiety and depression in patients with RAS .Fourty (40) patients with RAS and 40 age-matched controls were enrolled in this study. Blood and salivary levels were analyzed electrochemiluminescence technique. The Beck Depression Rating Scale (BDRS) and Beck Anxiety Scale (BAS), Perceived Stress Scale (PSS), and State-Trait Anxiety Inventory (STAI-S and STAI-T) were applied to all participants. There was no statistically significant differences levels between two groups regarding to BDRS, BAS, PSS, STAI-S and STAI-T level. Blood cortisol levels were statistically significantly higher in patients with RAS than controls (12.45 ± 0.74 μg/dL vs. 9.8± 0.68,respectively,p=0.01), wheras there was no statistically significant difference between women with RAS than controls regarding to salivary cortisol levels (0.33± 0.03 μg/dL vs. 0.34± 0.03, respectively. Patients with RAS have not higher depression and anxiety levels compared to the control.

___

1. Ship JA, Chavez EM, Doerr PA, et al. Recurrent aphthous stomatitis. Quintessence Int. 2000;31:95-112.

2. Vincent SD, Lilly GE. Clinical, historic and therapeutic features of aphthous stomatitis. Oral Surg Oral Med Oral Pathol. 1992;74:79-86.

3. Feng J, Zhou Z, Shen X, et al. Prevalence and distribution of oral mucosal lesions: A cross-sectional study in Shanghai, China. J Oral Pathol Med 2015;44:490-4.

4. Belenguer- Guallar I, Jiménez-Soriano Y, Ariadna Claramunt-Lozano A. Treatment of recurrent aphtous stomatitis. A literature review. J Clin Exp Dent. 2014;6:168–74.

5. Wray D, Graykowski EA, Notkins AL. Role of mucosal injury in initiating recurrent aphthous stomatitis. Br Med J (Clin Res Ed). 1981;283:1569–70.

6. Liang MW, Neoh CY. Oral aphthosis: management gaps and recent advances. Ann Acad Med Singap. 2012;41:463–70.

7. Huling LB, Baccaglini L, Choquette L et al. Effect of stressful life events on the onset and duration of recurrent aphthous stomatitis. J Oral Pathol Med 2012;41:149–52.

8. Spielberger CD, Gorsuch RL, Lushene RE. STAI: Manual for the State-Trait Anxiety Inventory. Palo Alto: Consulting Psychologists Press. 1970;120-6.

9. Beck AT, Beamesderfer A Assessment of depression: The Depression Inventory. In Pichot P edition. Psychological measurements in psychopharmacology. Karger. 1974;151-69.

10. Beck AT, Epstein N, Brown G et al. An inventory for measuring clinical anxiety: Psychometric properties. J Consulting Clin Psychol.1988;56:893-7.

11. Kim HJ, Park EH. Diagnostic efficiency of BDI in a clinical setting: comparison among depression, anxiety, psychosis and control group. Int J Innov Managd Technol. 2010;1:502-6.

12. McCartan BE, Lamey PJ, Wallace AM. Salivary cortisol and anxiety in recurrent aphthous stomatitis. J Oral Pathol Med 1996;25:357-9.

13. Soto Araya M, Rojas Alcayaga G, Esguep A. Association between psychological disorders and the presence of Oral lichen planus, Burning mouth syndrome and Recurrent aphthousbstomatitis. Med Oral. 2004;9:17.

14. Cohen L. Etiology, pathogenesis and classifications of aphthous stomatitis and Behçet’s syndrome. J Oral Pathol. 1978;7:347-52.

15. Dhopte A, Naidu G, Singh-Makkad R et al. Psychometric analysis of stress, anxiety and depression in patients with recurrent aphthous Stomatitis-A cross-sectional survey based study . J Clin Exp Dent. 2018;10:1109-14.

16. Gallo C B, Mimura MA, Sugaya NN. Psychological stress and recurrent aphthous stomatitis. Clinics (Sao Paulo) 2009;64:645–8.

17. Zadik Y, Levin L, Shmuly T et al. Recurrent aphthous stomatitis: Stress, trait anger and anxiety of patients. J Calif Dent Assoc. 2012;40:879–83.

18. Keenan AV, Spivakovksy S. Stress associated with onset of recurrent aphthous stomatitis. Evid Based Dent. 2013;14:25.

19. Suresh KV, Shenai P, Chatra L et al. Oral mucosal diseases in anxiety and depression patients: Hospital based observational study from south India. J Clin Exp Dent. 2015;7:95-9.

20. Varkal MD, Uyar ET, Bilal N et al. Anxiety levels and parental bonding in recurrent aphthous stomatitis patients. Bulletin of Clinical Psychopharmacology. 2015;25:45-6.

21. Karthikeyan P, Aswath N, Stress as an etiologic co-factor in recurrent aphthous ulcers and oral lichen planus. Journal of Oral Science. 2016;58:237-40.

22. Albanidou-Farmaki E, Poulopoulos AK, Epivatianos A, et al. Increased anxiety level and high salivary and serum cortisol concentrations in patients with recurrent aphthous stomatitis. Tohoku J Exp Med. 2008;214:291-6.

23. Eguia-del Valle A, Martínez-Conde-Lamosas R, López-Vicente J et al. Salivary cortisol determination in patients from the Basque Country with recurrent aphthous stomatitis. A pilot study. Med Oral Patol Oral Cir Bucal. 2013;1:207-11.

24. Nadendla LK, Meduri V, Paramkusam G et al. Relationship of salivary cortisol and anxiety in recurrent aphthous stomatitis. Indian J Endocrinol Metab. 2015;1:56-9.

25. Polat C, Düzer S, Ayyıldız H et al. Association Between Anxiety, Depression, and Salivary Cortisol Levels in Patients with Recurrent Aphthous Stomatitis Turk Arch Otorhinolaryngol. 2018;56:166-9.

26. Andrews VH, Hall HR. The effects of relaxation/imagery training on recurrent aphthous stomatitis: a preliminary study. Psychosom Med. 1990;52:526-35.

27. Zwiri AM. Anxiety, Depression and Quality of Life among Patients with Recurrent Aphthous Ulcers. J Contemp Dent Pract. 2015;16:112.

28. Sherman JJ, Barach R, Whitcomb KK, et al. Pain and pain-related interference associated with recurrent aphthous ulcers. J Orofac Pain. 2007;21:99-106.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: 4
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
Sayıdaki Diğer Makaleler

Disturbed sleep quality and increased depression scores in alopecia areata patients

Aynure OZTEKİN, Coskun OZTEKİN

Surgeon factor in pediatric supracondylar humerus fractures

Ali YUCE, Niyazi IGDE, Yunus IMREN, Suleyman Semih DEDOGLU, Hakan GURBUZ

Evaluation of helicobacter pylori eradication therapy with serum myeloperoxidase levels

Meside GUNDUZOZ, Servet Birgin IRİTAS, Servet GURESCİ, Murat BUYUKSEKERCİ, Osman Gokhan OZAKİNCİ, Yasar NAZLİGUL

The effect of gestational hypertension on the maternal mean platelet volume

Emre BASER, Funda SALGUR, Melek BİLGE, Safak OZDEMİRCİ, Eylem UNLUBİLGİN, Ozlem Moraloglu TEKİN, Deniz ESİNLER, Aykan YUCEL

Antioxidant and anti-lipoxygenase activities of Cydonia oblonga

Mehmet BERKOZ

Anesthesia management for emergency cesarean section in a patient with takotsubo cardiomyopathy

Sedat HAKİMOGLU, Onur KOYUNCU, Cagla AKKURT, Sumeyra YESİL, Senem URFALİ

Functional evaluation of bilateral arthroereisis of subtalar joint and simultaneousgastrocnemius lengthening in symptomatic flexible flatfoot in children

Zafer ATBASİ

Assessment of the clinical and sociodemographic characteristics of children and adolescents who are sent to an affiliated university hospital for forensic psychiatric examination

Yusuf OZTURK, Burcu Rahsan ERİM

The effects of anaesthesia induction with propofol or ketofol on cerebral oxygenation in patients above 60 years of age

Harun Tolga DURAN, Ersin KOKSAL, Yasemin Burcu USTUN, Sezgin BİLGİN, Fatih OZKAN

Histopathological gastric mucosal changes in patients using proton pump inhibitors

Saadet ALAN, Ayse Nur AKATLİ