Russell body cervicitis: A case report and literature review

Russell bodies are prominent eosinophilic inclusions seen in the cytoplasm of plasma cells and sometimes outside the cell. There are very few publications available in the English literature on Russell Body Cervicitis. Our case is a 40 year old female patient with a positive screening test for HPV DNA. The cervical surface epithelium in biopsy specimens obtained from the cervix completely have eroded intense vesicular eccentric nuclei and large eosinophilic cytoplasm containing focal Russell Body. The infiltration of dense plasma cells were observed. Our case is the fourth case in the English literature. The case is rare and the etiology has not yet been elucidated.

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Marmar JL, Gisser S, Praiss DE, Debenedictis TJ. The identification of functioning plasma cells in cervical tissue by an immunoperoxidase technique. Int J Fertil. 1981;26(1):25-9.

Edwards JNT, Morris HB. Langerhans’ cells and lymphocyte subsets in the female genital tract. Br J Obstet Gynaecol. 1985;92(9):974-82.

Stewart CJR, Leake R. Reactive plasmacytic infiltration with numerous Russell bodies involving the uterine cervix: ‘Russell body cervicitis’. Pathology. 2006;38(2):177-9.

Munsick RA, Janovski NA. Russell’s bodies in endocervical polyps. Obstet Gynecol. 1963;21:471-6.

Erbersdobler A, Petri S, Lock G. Russell body gastritis: an unusual, tumorlike lesion of the gastric mucosa. Arch Pathol Lab Med. 2004;128:915-7

Hsu SM, Hsu PL, McMillan PN, Fanger H. Russell bodies: a light and electron microscopic immunoperoxidase study. Am J Clin Pathol. 1982;77:26-31.

Cambruzzi E, Pêgas KL, Laus FF. Russell body gastritis: case report. J Bras Patol Med Lab. 2012;48(1):41-4.

Wolkersdörfer GW, Haase M, Morgner A, Baretton G, Miehlke S. Monoclonal gammopathy of undetermined significance and Russell Body formation in Helicobacter pylori gastritis. Helicobacter. 2006;11:506-10.

Tazawa K, Tsutsumi Y. Localized accumulation of Russell body-containing plasma cells in gastric mucosa with Helicobacter pylori infection: “Russell body gastritis”. Pathol Int. 1998;48:242-4.

Iwamoto T, Witmer R. Light and electron microscopy on plasma cells and Russell bodies in the iris of a chronic uveitis patient. Investigative Ophthalmology & Visual Science. 1969;8;563-82.

Rangan A, Visscher DW. Mott cell (Russell body) Barrett’s esophagitis. Leading the way in experimental and clinical research in hematology; Blood. 2016;128(15):1992

Zerosi C, Giardino L, Lafornara D, Scarola V. Presence of russell bodies in chronic dental pulp inflammation. Minerva Stomatologica.1999;48(7-8):307-10.

Erbersdobler A, Petri S, Lock G. Russell body gastritis: an unusual, tumorlike lesion of the gastric mucosa. Archives of Pathology & Laboratory Medicine. 2004;128(8): 915-7.

Rubio CA. Mott Cell (Russell Bodies) Barrett’s Oesophagitis. International journal of experimental and clinical pathophystology and drug research. 2005;19(6):1097-100.

Savas B, Ensari A, Heper AO, Kuzu Işınsu, Idilman R. An unusual presentation of helicobacter pylori infection: so-called “Russell body gastritis”. One-stop clinical resource for pathologists. 2005;446(4);463-6

Drut R, Olenchuk AB. Images in pathology. Russell body gastritis in an HIVpositive patient. Int J Surg Pathol. 2006;14(2):141-2.

Wolkersdörfer GF, Haase M, Morgner A, Baretton G, Miehlke S. Monoclonal gammopathy of undetermined significance and russell body formation in helicobacter pylori gastritis. Helicobacter. 2006;11(5);506-10.

Pizzolitto S, Camilot D, DeMaglio G, Falconieri G. Russell body gastritis: expanding the spectrum of Helicobacter pylori - related diseases? Pathol Res Pract. 2007;203(6);457-60.

Salmo E, Farroha M. Russell body cervicitis: Report of a case and review of the literatüre. The Internet Journal of Pathology. 2007; 7(1).

Verheij J, Jaspars EH, Valk PVD, Rozendaal L. Russell bodies in a skin biopsy: a case report. J Med Case Rep. 2009;3:108

Habib C, Gang DL, Ghaoui R, Pantanowitz L. Russell body gastritis. Am J Hematol.2010;85(12); 951-2.

Midi A, Çelikel ÇA, Kaya H. ‘Russell Body’ Gastritis: a case report. Turkish Journal of Pathology. 2010;26(2):159-61.

Coyne JD, Azadeh B. Russell body gastritis. Int J Surg Pathol. 2012;20(1):69-70.

Savage NM, Fortson T, SchubertM, Chamberlain S, Lee J, Ramalingam P. Isolated Russell body duodenitis. Dig Dis Sci. 2011;56(7);2202-4.

Wolf EM, Mrak K, Tschmelitsch J, Langner C. Signet ring cell cancer in a patient with Russell body gastritis – a possible diagnostic pitfall. Histopathology. 2011;58(7);1178-80.

Cambruzzi E, Pêgas KL, Laus F, Laus F. Russell body gastritis: case report. J. Bras. Patol. Med. Lab. 2012;48(1):41-4.

Choi J, Lee HE, Byeon SJ, Nam KH, Kim MA, Kim WH. Russell body gastritis presented as a colliding lesion with a gastric adenocarcinoma: A case report. Basic and Applied Pathology. 2012;5(2);54-7.

Bhalla A, Mosteanu D, Gorelick S, Hani-el-Fanek. Russell body gastritis in an HIV positive patient: case report and review of literature. Conn Med. 2012;76(5):261-5.

Miura S, Shirahama K, Sakaguchi M, Takao M, Hirakawa T, Nishihara M, Shimada M, Oka H, Ishiguro S. An example of Russell’s body was diagnosed with gastritis. Nihon Shokakibyo Gakkai Zasshi. 2012;109(6):929-35

Yoon JB, Lee TY, Lee JS, Yoon JM, Jang SW, Kim MJ, Lee SJ, Kim TO. Two Cases of Russell Body Gastritis Treated by Helicobacter pylori Eradication. Clin Endosc. 2012;45:412-6.

Araki D, Sudo Y, Imamura Y, Tsutsumi Y. Russell body gastritis showing IgM kappa-type monoclonality. Pathol Int. 2013;63(13);565-7.

Bhaijee F, Brown KA, Long BW, Brown AS. Russell Body Gastroenteritis: An aberrant manifestation of chronic inflammation in gastrointestinal mucosa. Case Rep Med. 2013;2013:797264.

Chen D, Thota P, Liu X. Isolated russell body duodenitis with concurrent helicobacter pylori gastritis. J Med Cases. 2013;4(3):166-9.

Lee JS, Kim EU, Park SJ, Nam KW, Bae SH, Kim EJ, Song HJ, Lee GH, Jung HY, Kim JH. Regression of russellbody gastritis after helicobacter pylori eradication. The Korean Journal of Helicobacter and Upper Gastrointestinal Research. 2013;13(3):189-93.

Takahashi Y, Shimizu S, Uraushihara K, Fukusato T. Russell body duodenitis in a patient with retroperitoneal metastasis of ureteral cancer. World J Gastrointest Endosc. 2013;19(1):125-8.

Foda AAM, Shalaby AA, El-Hawary AK. Russell body cervicitis: a case report. J Clin Pathol. 2014;2(1):109-11.

Muthukumarana V, Segura S, O’Brien M, Siddiqui R, El-Fanek H. “Russell body gastroenterocolitis” in a posttransplant patient: A case report and review of literature. Int J Surg Pathol. 2015;23(8):667-72.

Munday WR, Kapur LH, Xu M, Zhang X. Russell body duodenitis with immunoglobulin kappa light chain restriction. World J Gastrointest Endosc 2015;7(1):73-6.

Antunes AG, Cadillá J, Velasco F. Russell body gastritis in an Hp-negative patient. BMJ Case Rep. 2016;10;2016. pii: bcr2016216717.

Coates RF, Ferrentino N, Yang MX. Russell body inflammatory polyp a case report and review of literature. Int J Surg Pathol. 2017;25(1):94-9

Goto A, Okamoto T, Matsumoto M, Saito H, Yanai H, Itoh H, Sakaida I. Chronological endoscopic and pathological observations in russell body duodenitis. Clin Endosc. 2016;49(4):387–90.

Nishimura N, Mizuno M, Shimodate Y, Doi A, Mouri H, Matsueda K, Yamamoto H, Notohara K. Russell body gastritis treated with helicobacter pylori eradication therapy: Magnifying endoscopic findings with narrow band imaging before and after treatment. ACG Case Rep J. 2016;3(4):e96

Zhang M, Li Q, Qu JL, Li L, Zhang W. Russell body gastritis: report of a case. Zhonghua Bing Li Xue Za Zhi. 2016;45(12):881-2.

Kurihara K, Sakai H, Hashimoto N. Russell, oral B-lenfomalarda gövde benzeri inklüzyonlar. J Oral Pathol. 1984;13(6):640-9.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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