Increased serum levels of Bisphenol A and Betatrophin in patients with Psoriasis

Psoriasis is a common and serious systemic inflammatory disease. The purpose of this study is to research the relationship between bisphenol A, betatrophin, urocortin 3 and vitamin D levels in patients with psoriasis. Sixty patients with psoriasis (mean age, 34.1±9.6 years) and twenty six age and gender-matched healthy individuals (mean age, 35.5 ±10.5 years) were included in this study. Bisphenol A, betatrophin, urocortin 3 and vitamin D levels were assessed by using enzyme-linked immunosorbent assay in all participants. Serum levels of bisphenol A were detected using UPLC-ESI-MS/MS. In psoriasis patients, the median bisphenol A serum level was 0.537 ng/mL (range 1.1), and significantly higher compared to controls (median 0.2 range 0.9 ng/mL) (p

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Melikoglu M. Sleep Quality and its Association with Disease Severity in Psoriasis. Eurasian J Med. 2017;49:124-7.

Kumar P, James W. Psoriasis, Plaque. StatPearls. Treasure Island. 2017.

Balci DD, Balci A, Karazincir S, et al. Increased carotid artery intima-media thickness and impaired endothelial function in psoriasis. J Eur Acad Dermatol Venereol. 2009;23:1-6.

Neimann AL, Shin DB, Wang X, et al. Prevalence of cardiovascular risk factors in patients with psoriasis. J Am Acad Dermatol. 2006;55:829-35.

Jurgen Schauber, Richard L, Gallo. The vitamin D pathway: a new target for control of the skin’s immune response? Exp Dermatol. 2008;17:633-9.

Crujeiras AB, Zulet MA, Abete I, et al. Interplay of atherogenic factors, protein intake and betatrophin levels in obese-metabolic syndrome patients treated with hypocaloric diets. Int J Obes. 2016;40:403-10.

Gisondi P, Ferrazzi A, Girolomoni G. Metabolic comorbidities and psoriasis. Acta Dermatovenerol Croat. 2010;18:297-304.

Gisondi P, Galvan A, Idolazzi L, et al. Management of moderate to severe psoriasis in patients with metabolic comorbidities. Front Med. 2015;2:1

Bajaj DR, Mahesar SM, Devrajani BR, et al. Lipid profile in patients with psoriasis presenting at Liaquat University Hospital Hyderabad. J Pak Med Assoc. 2009;59:512-5.

Mysliwiec H, Baran A, Harasim-Symbor E, et al. Serum fatty acid profile in psoriasis and its comorbidity. Arch Dermatol Res. 2017;309:371-80.

Aytekin A, Togral AK, Yilmaz ÖH. Epoxy Resins and the Relationship with Occupational Dermatoses. Ankara Med J. 2015;15:96-101.

Zangeneh FZ, Fazeli A. The significance of stress hormones in psoriasis. Acta Medica Iranica. 2008;46:485-8.

Singh LK, Boucher W, Pang X, et al. Potent mast cell degranulation and vascular permeability triggered by urocortin through activation of corticotropin-releasing hormone receptors. J Pharmacol Exp Ther. 1999;288:1349-56.

Hannen R, Udeh-Momoh C, Upton J, et al. Dysfunctional Skin-Derived Glucocorticoid Synthesis Is a Pathogenic Mechanism of Psoriasis. J Invest Dermatol. 2017;137:1630-7.

Reich A, Wójcik-Maciejewicz A, Slominski AT. Stress and the skin. G Ital Dermatol Venereol. 2010;145:213-9.

Slominski A, Zbytek B, Nikolakis G,et al. Steroidogenesis in the skin: implications for local immune functions. J Steroid Biochem Mol Biol. 2013a;137:107-23.

Mehmood ZH, Papandreou D. An updated mini review of vitamin D and obesity: Adipogenesis and inflammation state. Open Access Maced J Med Sci. 2016;4:526–32.

Zhang Y, Leung DY, Richers BN, et al. Vitamin D inhibits monocyte/ macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. J Immunol. 2012;188:2127–35.

Neve A, Corrado A, Cantatore FP. Immunomodulatory effects of vitamin D in peripheral blood monocyte-derived macrophages from patients with rheumatoid arthritis. Clin Exp Med. 2014;14:275-83.

Wadhwa B, Relhan V, Goel K, et al. Vitamin D and skin diseases: A review. Indian J Dermatol Venereol Leprol. 2015;81:344-55.

Barrea L, Savanelli MC, Di Somma C, et al. Vitamin D and its role in psoriasis: An overview of the dermatologist and nutritionist. Rev Endocr Metab Disord. 2017;18:195-205.

Richetta AG, Silvestri V, Giancristoforo S, et al. A-1012G promoter polymorphism of vitamin D receptor gene is associated with psoriasis risk and lower allele-specific expression. DNA Cell Biol. 2014;33:102–9.

Byung-Soon Park, Jeong-Soo Park, Dong-Youn Lee, et al. Vitamin D Receptor Polymorphism is Associated with Psoriasis. J Invest Dermatol. 1999;112:113-6.

Coimbra S, Oliveira H, Neuparth MJ, et al. Metabolic syndrome in psoriasis patients. Residual inflammation and pro-inflammatory IL17 signaling reduce length of remission. A follow-up study. Br J Dermatol. 2015;174:414-6.

Boehncke WH, Boehncke S, Tobin AM, et al. The ‘psoriatic march’: a concept of how severe psoriasis may drive cardiovascular comorbidity. Exp Dermatol. 2011;20:303-7.

. Shlyankevich J, Mehta NN, Krueger JG, et al. Accumulating evidence for the association and shared pathogenic mechanisms between psoriasis and cardiovascular-related comorbidities. Am J Med. 2014;127:1148-53.

Mattozzi C, Paolino G, Salvi M, et al. Correlation between plasmatic levels of Vitamin D and PASI score: our experience and mini-review of the literature. G Ital Dermatol Venereol. 2018;153:155-60.

Rodríguez-Zúñiga MJM, García-Perdomo HA. Systematic review and meta analysis of the association between psoriasis and metabolic syndrome. J Am Acad Dermatol. 2017;77:657-666.e8.

Fenzl A, Itariu BK, Kosi L, et al. Circulating betatrophin correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulinresistant individuals. Diabetologia. 2014;57:1204-8.

Fu Z, Abou-Samra AB, Zhang R. An explanation for recent discrepancies in levels of human circulating betatrophin. Diabetologia. 2014;57:2232-4.

Alper S, Akyol M, Atakan N, et al. Turkish Guideline for the Treatment of Psoriasis. Turkderm. 2012;46:1

Theoharides TC, Donelan JM, Papadopoulou N, et al. Mast cells as targets of corticotropin-releasing factor and related peptides. Trends Pharmacol Sci. 2004;25:563-8.

Gupta MA, Gupta AK. Age and gender differences in the impact of psoriasis on quality of life. Int J Dermatol. 1995;34:700-3. 3

Andrzej T. Slominski, Michal A. Zmijewski, Blazej Zbytek, et al. Theoharides, and Jean Rivier. Key Role of CRF in the Skin Stress Response System. Endocr Rev. 2013;34:827-84.

Choi EH, Brown BE, Crumrine D, et al. Mechanisms by which psychologic stress alters cutaneous permeability barrier homeostasis and stratum corneum integrity. J Invest Dermatol. 2005;124:587-95.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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