Incidentally Detected Myocardial Cleft: Cardiac Computed Tomography and Magnetic Resonance Imaging Findings

Myocardial clefts are congenital anomalies, usually localized in the basal inferior wall of the left ventricle and mid-apical segments of the interventricular septum. The patients with genetic mutations related to hypertrophic cardiomyopathy showed significant elevation in the incidence of myocardial cleft. Also there is a significant correlation between the myocardial clefts and the carriers of hypertrophic cardiomyopathy gene mutations without clinical signs. Magnetic resonance imaging allows us to diagnose the myocardial clefts of the healthy individuals as well as the patients and closely follow up for clinical hypertrophic cardiomyopathy. Here we present the cardiac computed tomography and magnetic resonance imaging findings of a case with myocardial cleft

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1. Germans T, Wilde AA, Dijkmans PA, Chai W, Kamp O, Pinto YM, van Rossum AC. Structural abnormalities of the inferoseptal left ventricular wall detected by cardiac magnetic resonance imaging in carriers of hypertrophic cardiomyopathy mutations. J Am Coll Cardiol. 2006;48(12):2518-23.

2. Afonso L, Kottam A, Khetarpal V. Myocardial cleft, crypt, diverticulum, or aneurysm? Does it really matter? Clin Cardiol. 2009;32:48-51.

3. Johansson B, Maceira AM, Babu-Narayan SV. Clefts can be seen in the basal inferior wall of the left ventricle and the interventricular septum in healthy volunteers as well as patients by cardiovascular magnetic resonance. J Am Coll Cardiol. 2007;50:1294-5.

4. Maron MS, Rowin EJ, Lin D, Appelbaum E, Chan RH, Gibson CM, Lesser JR, Lindberg J, Haas TS, Udelson JE, Manning WJ, Maron BJ. Prevalence and clinical profile of myocardial crypts in hypertrophic cardiomyopathy. Circ Cardiovasc Imaging. 2012;5(4):441-7.

5. Johansson B, Maceira AM, Babu-Narayan SV, Moon JC, Pennell DJ, Kilner PJ. Clefts can be seen in the basal inferior wall of the left ventricle and the interventricular septum in healthy volunteers as well as patients by cardiovascular magnetic resonance. J Am Coll Cardiol. 2007;50(13):1294-5.

6. Maron BJ, Maron MS. Hypertrophic cardiomyopathy. Lancet. 201319;381(9862):242-55.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: 4
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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