Berrak BİLGİNER GURBUZ, Fatih GURBUZ, Atilla CAYİR, İrfan Oguz SAHİN, Deniz OKDEMİR, Alev GUVEN, Aydan DEGERLİYURT, Gulsen KOSE

Evaluation of Neuroimaging and Electroencephalography Findings in Patients with Status Epilepticus [Status Epileptikus Tanısıyla İzlenen Hastaların Nörogörüntüleme ve EEG Bulgularının Değerlendirilmesi

AbstractStatus epilepticus (SE) is one of the most important pediatric emergent conditions because of major cause of morbidity and mortality. SE should be diagnosed and treated emergently, because it is one of the diseases that may lead to serious sequalea. The aim of the study is to evaluate neuroimaging methods and electroencephalography (EEG) findings of patients with SE, who were under follow up at our hospital. 162 patients (age range, 0-18 years) with SE treated and followed at our hospital between December 2006 and May 2009 were enrolled in our study. Patient’s age, sex, MRI- CT imaging and EEG findings were recorded from patient’s files. Patient’s age and sex were similar. CT was available in 41 patients and MRI was available in 36 patients. CT results of 28 patients were normal, but some pathologies were found in 13 patients. MRI results of 14 patients were normal, but some alterations were detected in 22 patients. EEG was present in 97 patients. EEG results of 49 patients (%50.5) were normal. Consequently, there is no enough data regarding the necessity of the use of neuroimaging methods in case of previous etiology-confirmed SE. However, neuroimaging methods may be considered useful to determinate etiology of SE, response to treatment, and effects on long-term prognosis. Moreover, we can highlight that the early period EEG may be important in determining prognosis. Keywords: Status epilepticus, children, neuroimaging, EEG

Anahtar Kelimeler:

Status epileptikus, çocuklar, nörogörüntüleme, EEG

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Kaynaklar
Pellock MJ. Status epilepticus. In: Swaiman K. F, Ashwal S, eds, Pediatric Neurology Principles and Practice, 3th Edition. St Louis: Mosby 1999;683-91.
Komur M, Arslankoylu AE, Okuyaz C, Keceli M, Derici D. Management of patients with status epilepticus treated at a pediatric intensive care unit in Turkey. Pediatr Neurol. 2012;46(6):382-6.
Bhalla A, Das B, Som R, Prabhakar S, Kharbanda PS. Status epilepticus: Our experience in a tertiary care centre in Northwestern India. J Emerg Trauma Shock. 2014;7:9-13.
Martinos MM, Yoong M, Patil S, Chong WK, Mardari R, Chin RF, Neville BG, de Haan M, Scott RC. Early developmental outcomes in children following convulsive status epilepticus: a longitudinal study. Epilepsia. 2013; 54(6):1012-9.
Holmes GR, Stafstrom CE. The Epilepsies. In: David BR, ed, Child and Adolescent Neurology. St Louis: Mosby. 1998;183-234.
Treiman MD. Status epilepticus. In: Wyllie E, ed, The Treatment of Epilepsy Principles and Practice, 3th, edition. Philadelphia: Lipincott Williams &Wilkins. 2001;681-97.
Evans OB. Manuel of Child Neurology. New York, Churchill Livingstone, 1987;403-7.
İcagasıoglu DF. Status epilepticus. Turkiye Klinikleri J Pediatr Sci. 2008;4(4):34-41.
Kaya U, Turanlı G. Status epileptikus. Katkı Pediatri Dergisi. 2008;30(6):749-66.
Chaure MR, Chin RFM, Neville BG, Bedford H, Scott RC. The epidemiology of convulsive status epilepticus in children: A critical review. Epilepsia. 2007;48(9):1652-63.
Guerrini R. Epilepsy in children. Lancet. 2006; 367(9509):499-524.
Aicardi J, Chevrie JJ. Convulsive status epilepticus in infants and children. Epilepsia. 1970;11(2):187-97.
Freilich ER, Schreiber JM, Zelleke T, Gaillard WD. Pediatric status epilepticus: identification and evaluation. Curr Opin Pediatr. 2014; 26(6):655-61.
Cartagena AM, Young GB, Lee DH, Mirsattari SM. Reversible and irreversible cranial MRI findings associated with status epilepticus. Epilepsy Behav. 2014; 33:24-30.
Berg AT, Testa FM, Levy SR, Shinnar S. Neuroimaging in children with newly diagnosed epilepsy: a community-based study. Pediatrics. 2000;106(3):527-32.
Meytal J, Krauss JM, Novak G, Nagelberg J, Patel M. The role of brain computed tomography in evaluating children with new onset of seizures in the emergency department. Epilepsia. 2000;41(8):950-4.
Doescher JS, deGrauw TJ, Musick BS, Dunn DW, Kalnin AJ, Egelhoff JC, Byars AW, Mathews VP, Austin JK. Magnetic resonance imaging and electroencephalographic findings in a cohort of normal children with newly diagnosed seizures. J Child Neurol. 2006; 21(6):491-5.
Singh RK, Stephens S, Berl MM, Chang T, Brown K, Vezina LG, Gaillard WD. Prospective study of new-onset seizures presenting as status epilepticus in childhood. Neurology 2010;74(8):636-42.
Stein SC, Hurst RW, Sonnad SS. Meta-analysis of cranial CT scans in children: a mathematical model to predict radiation-induced tumors: Pediatr Neurosurg 2008;44(6):448-57.
Meierkord H, Holtkamp M. Non-convulsive status epilepticus in adults: clinical forms and treatment. Lancet Neurol. 2007;6(4):329-39.
Nei M, Lee JM, Shanker VL, Sperling MR. The EEG and prognosis in status epilepticus. Epilepsia. 1999;40(2):157-63.