Gulsah ELBUKEN, Recep AKTİMUR, Kadir YİLDİRİM, Sude Hatun AKTİMUR, Mehmet Derya DEMİRAG, Aysu Basak OZBALCİ, Mustafa BAKİRTAS, Banu KİRTİLOGLU, Nuraydın OZLEM

Gulsah Elbuken1, Recep Aktimur2, Kadir Yildirim2, Sude Hatun Aktimur3, Mehmet

Anahtar Kelimeler:

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Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operatıve Serum Calcium and Alkaline Phosphatase Levels

AbstractThe aim of the present study was to determine the relationship between biochemical parameters, mean diameter of parathyroid adenoma (MDPA) and parathyroid hormone (PTH) levels in patients who underwent parathyroid surgery.Materials and Methods: Data were collected retrospectively from patients with hyperparathyroidism who were operated and followed in our hospital between September 2011 and April 2014. Twenty-nine (male/female = 8/21) patients with a mean age of 58.31 ± 12.59 years were enrolled into the study. The mean pre-operative serum calcium and intact PTH (iPTH) levels were 11.98±1.23 mg/dl and 386.52±374.96 pg/ml, respectively. Serum pre-operative calcium levels were found to be significantly higher in patients who had nephrolithiasis than those who did not, whereas pre-operative serum phosphate levels were lower. Pre-operative iPTH levels were found to be correlated with pre-operative calcium, alkaline phosphatase and MDPA but not with pre-operative serum phosphate. Also, pre-operative calcium levels were found to be significantly correlated with MDPA.Conclusion: Presence of nephrolithiasis is associated with higher pre-operative calcium and lower phosphate levels. Pre-operative iPTH and calcium levels were also found to be significantly correlated with MDPA; this suggests that serum iPTH and calcium levels can be useful in predicting MDPA. Keywords: Hypercalcemia, primary hyperparathyroidism, parathyroid adenoma, parathormone, calcium

Keywords:

Hypercalcemia, primary hyperparathyroidism, parathyroid adenoma, parathormone calcium,

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