PRİMER SJÖGREN SENDROMU OLAN HASTADA EROZİV ARTRİT: BİR OLGU SUNUMU
Primer Sjögren sendromu, sıklıkla ağız ve göz kuruluğu ile seyreden bir kronik otoimmun ekzokrinopatidir.Ağıziçi bezleri ve göz yaşı bezleri dışında, nadir de olsa diğer ekzokrin bezler de etkilenebilir. En sık kas-iskelet sistemtutuluşu ile karşımıza çıkmaktadır. Artralji, sabah tutukluğu ve romatoid artrite benzer kronik inflamatuvarpoliartrit, eklem bulgularını oluşturmaktadır. Romatoid artrit'ten farklı olarak, Sjögren sendromunda sabahtutukluğu ve hareket kısıtlığı daha hafif olup, el ve el bilek deformasyonları görülmektedir. Romatoid artrit'tenayıran en önemli özellik ise, direk grafi ve/veya magnetik rezonans görüntülerde, eklemlerde erozivdeğişikliklerin olmamasıdır. Bu bildiride, primer Sjögren sendromu tanısı almış hastada, eroziv artrit raporedilmiştir
Erosive arthritis in a Patient with Primary Sjogren's Syndrome: A Case Report
Primary Sjogren's syndrome (SS) is an autoimmune exocrinopathy characterized by dry eyes and dry mouth. Exocrine glands other than salivary and lacrimal glands may be affected less frequently. The most common mode of presentation is musculoskeletal system involvement. Articular signs and symptoms include arthralgias, morning stiffness, and chronic polyarthritis that resemble those seen in rheumatoid arthritis (RA). Compared with RA, the arthritis tends to be more relapsing and remitting, and stiffness is less marked. The distinction fromRAis that, there is not any erosive changes neither on direct radiography nor magnetic resonance imaging (MRI).We report a patient of primary SS presented with erosive arthritis.
___
- 1. Skopouli FN, Moutsopoulos HM. Autoimmune
epithelitis: Sjögren's syndrome. Clin Exper Rheum
1994;12(supplement 11):S9-S11.
- 2. Andonopoulos AP, Drosos AA, Skopouli FN, et al.
Secondary Sjögren's syndrome in rheumatoid arthritis.
J Rheumatol 1987;1:1098-103.
- 3. Pavlidis NA, Karsh J, Moutsopoulos HM. The clinical
Picture of primary Sjögren's syndrome: a retrospective
study. J Rheumatol 1982;9:685-90.
- 4. Chisholm DM, Mason DK. Labial salivary gland
biopsy in Sjögren's disease. J Clin Pathol 1968;21: 656-
60.
- 5. Boutry N, Hachulla E, Flipo R, et al. MR imaging
findings in hands in early rheumatoid arthritis:
comparison with those in systemic lupus
erythematosus and primary Sjögren syndrome.
Radiology 2005; 236: 593-600.
- 6. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos
HM, Alexander EL, Carsons SE et al (2002)
Classification criteria for Sjögren's syndrome: a
revised version of the European criteria proposed by
the American-European Consensus Group. Ann
Rheum Dis 61:554-8.
- 7. Agrawal S, Misra R, Aggarwal A. Autoantibodies in
rheumatoid arthritis: association with severity of
disease in established RA. Clin Rheumatol
2007;26(2):201-4.