MESANE KARSİNOMUNA SEKONDER JEJUNOVEZİKAL FİSTÜLE BAĞLI ŞİDDETLİ METABOLİK ASİDOZ

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Severe Metabolik Acidosis Secondary to Jejunovesical Fistula in a Patient with Carsinoma of the Urinary Bladder

Several complications can arise when intestinal mucosa comes in contact with urine in patients with urinary reconstruction using intestinal segments or intestinovesical fistulas. The most important ofthese complications is hyperchloremic metabolic acidosis. It has been shown that the acidosis is mainly a result of ammonium reabsorption with a much smaller contribution of bicarbonate secretion by intestinal mucosa. In this report, a patient with jejunovesical fistula secondary to carsinoma of the bladder with severe metabolic acidosis is presented and pathophysiology of the metabolic derangements is reviewed.

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  • 1. Fichtner J. Follow-up after urinary diversion. Urol Int 1999; 63: 40-5.
  • 2. Hall MC, Koch MO, Mc Dougal WS. Metabolic consequences of urinary diversion through intestinal segments. Urol Clin NorthAm 1991; 18: 425-35.
  • 3. Koch MO, McDougal WS. The pathophysiology of hyperchloremic metabolic acidosis after urinary diversion through intestinal segments. Surgery 1985; 98: 561.
  • 4. Koch MO, Gurevitch E, Hill DE et al. Urinary solute transport by intestinal segments: A comparative study of ileum and colon. J Urol 1990; 143: 1275.
  • 5. Filipas D, Fisch M, Abol Enein H, Fichtner J, Bockisch A, Hohenfelner R. Chloride absorption in patients with a continent ileocaecal reservoir (Mainz pouch I). Br J Urol 1997; 79: 588-91.
  • 6. Stein R, Fisch M, Andreas J, Bockisch A, Hohenfellner R, Thuroff JW. Whole-body potasssium and bone mineral density up to 30 years after urinary diversion. Br J Urol 1998; 82:798-803.
  • 7. Klein EA, Montie JE, Montague D, et al. Jejunal conduit urinary diversion. J Urol 1986; 135:244.
  • 8. Stampfer DS, McDougal WS, McGovern FJ. The use of bowel in urology: Metabolic and nutritional complications. Urol Clin NorthAm 1997; 24: 715-22.