Abdülkerim Furkan TAMER, Habib EMRE, Levent KORKMAZ, Erim Gülcan, Refik Ali SARI, Abdullah UYANIK, Mustafa Keleş

Lökositoklastik Vaskülit Olarak Gelen Bir Olguda Nefrotik Sendrom Nedeni: Fokal Segmental Glomerüloskleroz

Lökositoklastik vaskulit vücuttaki küçük damarların inflamasyonu anlamına gelmektedir. Genellikle ciltte özellikle bacaklarda belirti verir ancak vücudun diğer bölgelerinde de ortaya çıkabilir. Klinik pratikte en yaygın görülen vaskulittir. Lökositoklastik vaskulit pek çok nefrolojik hastalıklarla birlikte seyredebilir. Ancak lökositoklastik vaskulit olarak gelen nefrotik sendromlu hastada fokal segmental glomerüloskleroz görülmesi beklenmeyen bir durumdur. Fokal segmental glomerülosklerozda glomerüler hasara ve glomerüloskleroza yol açan etyolojik ajanlar veya mekanizmaların çoğu bilinmemektedir. Onsekiz yaşında her iki üst ve alt ekstremitelerde döküntü ve kızarıklık, her iki bacaklarda şişlik şikayetleri ile kliniğimize başvuran hastaya lökositoklastik vaskulit tanısı konuldu. Nefrotik düzeyde proteinürisi olan hastanın böbrek biyopsisinde ise fokal segmental glomeruloskleroz tespit edildi

Anahtar Kelimeler:

: Fokal segmental glomerüloskleroz, lökositoklastik vaskulit, nefrotik sendrom

Cause of Nephrotıc Syndrome at A Case Admitted About Leukocytoclastic Vasculitis: Focal Segmental Glomerulosclerosis

Leukocytoclastic vasculitis refers to the inflammation of small blood vessels in the body. It usually manifests in the skin, particularly in the legs, but it may also occur in other areas. It is the most common vasculitis seen in clinical practice. Leukocytoclastic vasculitis can progress together with many nephrological diseases. However, focal segmental glomerulosclerosis is unexpected cause of nephrotic syndrome at a case admitted about leukocytoclastic vasculitis. Etiologic agents or mechanisms that initiate glomerular injury and lead to glomerulosclerosis are largely unknown in focal segmental glomerulosclerosis. An eighteen years old patient who presented to our clinic with skin eruption and rushes of both lower and upper extremities and edema of lower extermities had been diagnosed leukocytoclastic vasculitis. The patient with nephrotic range proteinuria, renal biopsy reveal.

Keywords:

Focal segmental glomerulosclerosis, leukocytoclastic vasculitis, nephrotic syndrome,

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