NESRİN HAŞİMİ, ABDULSELAM ERTAŞ, Elif VARHAL ORAL, MEHMET HÜSEYİN ALKAN, MEHMET BOĞA, MUSTAFA ABDULLAH YILMAZ, İSMAİL YENER, IŞIL GAZİOĞLU, Cumali Özaslan, Mehmet AKDENİZ, UFUK KOLAK

Chemical Profile of Malva Neglecta and Malvella Sherardiana by LcMS/MS, GC/MS and Their Anticholinesterase, Antimicrobial and Antioxidant Properties With Aflatoxin-Contents

The purpose of the present work was to calculate the phenolic and the fatty acids profiles by LC-MS/MS and GC/MS with their antioxidant, anticholinesterase and antimicrobial activities, and aflatoxin contents of Malva neglecta and Malvella sherardiana. The phenolic contents of M. neglecta and M. sherardiana were determined by LC-MS/MS. Malic and 4-OH benzoic acids were found to be the most abundant compounds in M. neglecta and M. sherardiana, respectively. On the other hand, essential oils and fatty acids composition were determined by GC/MS analysis. The methanol extracts of the plants showed the highest effect in all antioxidant assays of this study. The methanol extract of M. neglecta showed the highest activity among the petroleum ether, acetone, methanol and water extracts against acetyl- and butyryl- cholinesterase enzymes (53.68% and 63.95% inhibition ratio, respectively). The acetone extracts of M. neglacta and M. sherardiana exhibited moderate activity against C. albicans with 18 and 17 mm inhibion zone diameter, respectively. The results of the present study is also showed that the M. neglecta and M. sherardiana can also be used as a food source due to its high phenolic acid content and good antioxidant property. Also, the samples were aflatoxin free.

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