Özlem Devrim BALABAN, Gizem BOZ, Kumru ŞENYAŞAR, Menekse Sila YAZAR, ALİ KEYVAN, Nezih ERADAMLAR

The olfactory reference syndrome treated with escitalopram: A case report

Olfaktör referans sendromu (ORS), hastaların diğer insanlar için rahatsız edici olabilecek nitelikte kötü kokular yaydıkları konusunda oldukça endişeli olduğu klinik bir durumdur. Bu durum, şiddetli stres ve depresyona sebep olup, intihara bile yol açabilmektedir. Olfaktör referans sendromu, sınıflandırma sistemlerinde ve literatürde farklı kategoriler altında değerlendirilmektedir. Bu yazıda, essitalopram ile tedavi edilen, anal bölgesinden kaynaklanan kötü kokular yaydığına dair preoküpasyonları olan bir ORS vakasını ve bu vaka çercevesinde ORSnu, sınıflandırma sistemlerinde ve literatürde farklı kategoriler altında tartıştık.

Essitalopram ile tedavi edilen bir olfaktör referans sendromu : Bir olgu sunumu

Olfactory reference syndrome (ORS) is a clinical condition that causes patients to be excessively anxious about emitting body odors that may be offensive for other people. This causes heavy distress and depression, even leading to suicides. The ORS is classifised under different categories. In this paper, we report a patient with ORS. She has a preoccupation of foul body odor emanating from her anal region which we treated with escitalopram. We also discuss, within the framework of this case, the place of ORS in systems of clinical classified and in literature.

PDF

___

1. Pryse-Phillips W. An olfactory reference syndrome. Acta Psychiatr Scand 1971;47:484509.
2. Munro A. Monosymptomatic hypochondriacal psychosis. Br J Psychiatry Suppl. 1988 Jul; (2):37-40.
3. Begum M, McKenna PJ. Olfactory reference syndrome: a systematic review of the world literature. Psychol Med 2011;41:453-61. doi: 10.1017/S0033291710001091.
4. Cruzado L, Cáceres-Taco E, Calizaya JR. Apropos of an Olfactory Reference Syndrome case. Actas Esp Psiquiatr 2012; 40:234-8.
5. Stein DJ, Le Roux L, Bouwer C, Van Heerden B. Is olfactory reference syndrome an obsessive-compulsive spectrum disorder? Two cases and a discussion. J Neuropsychiatry Clin Neurosci 1998;10:96-9.
6. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th edition. Washington, DC: American Psychiatric Association, 1994.
7. Phillips KA, Menard W. Olfactory reference syndrome: demographic and clinical features of imagined body odor. Gen Hosp Psychiatry 2011;33:398-406. doi: 10.1016/j. genhosppsych.2011.04.004.
8. Phillips KA, Gunderson C, Gruber U. Delusions of body malodour; the olfactory reference syndrome. In: Brewer W, Castle D, Pantelis C, editors. Olfaction and the Brain. New York:Cambridge: University Press, 2006:34353.
9. Puşuroğlu M, Kandemir G, Hocaoğlu Ç. Ergende olfaktör referans sendromu: Bir olgu sunumu. JMOOD 2014; 4:41-3. doi: 10.5455/jmood.20131119012825.
10. Bizamcer AN, Dubin WR, Hayburn B. Olfactory reference syndrome. Psychosomatics 2008; 49:77-81. doi: 10.1176/appi. psy.49.1.77.
11. Suzuki K, Takei N, Iwata Y, et al. Do olfactory reference syndrome and jiko-shu-kyofu (a subtype of taijin-kyofu) share a common entity? Acta Psychiatr Scand 2004;109:150-5. doi: 10.1046/j.1600-0447.2003.00195
12. Prazeres AM, Fontenelle LF, Mendlowicz MV, et al. Olfactory reference syndrome as a subtype of body dysmorphic disorder. J Clin Psychiatry 2010 ;71:87-9. doi: 10.4088/JCP.09l05040.
13. Teraishi T, Takahashi T, Suda T, et al. Successful treatment of olfactory reference syndrome with paroxetine. J Neuropsychiatry Clin Neurosci 2012 ;24:E24. doi:10.1176/ appi.neuropsych.11020033.
14. Martin-Pichora AL, Antony MM. Successful treatment of olfactory reference syndrome with cognitive behavioral therapy: A case study. Cognitive and Behavioral Practice 2011;18: 545-54. doi: 10.1016/j.cbpra.2010.11.007.