The effect of anaesthetic technique on postoperative venous thromboembolism in elderly patients undergoing total hip replacement

Amaç: Yaşlı hastalarda sık görülen travmatik kalça kırığının major tedavisi total kalça protezidir. Ancak bu girişim venöz tromboemboli gibi belirgin postoperatif komplikasyonlara neden olabilir. Bu çalışmada travmatik kalça kırığı nedeniyle total kalça protezi operasyonu geçiren yaşlı hastalarda postoperatif dönemde morbidite ve mortaliteyi arttıran bir komplikasyon olan venöz tromboemboli görülme sıklığının uygulanan anestezi yöntemiyle ilişkisi retrospektif olarak incelenmiştir. Gereç ve Yöntem: Kliniğimizde 1997-2003 tarihleri arasında 65 yas uzeri, travmatik kalça kırığı nedeniyle total kalça protezi operasyonu geçiren 65 yas ustu hastalarin kayitlari incelenmistir. Hastalarin demografik özellikleri, intraoperatif ve postoperatif bulguları, venöz tromboemboli görülme sıklığı ve anestezi yontemi ile ilişkisi incelenmiştir. Bulgular: 291 hastanın %10.8’inde postoperatif venöz tromboemboli tesbit edilmiştir. Genel anestezi sonrası tromboemboli sıklığı %10.5 iken, epidural anestezi sonrası %9.2 olarak belirlenmiştir (p>0.05). Sonuçlar: Çalışmamızda venöz tromboemboli sıklığı ile cerrahi sırasında uygulanan anestezi yöntemi arasında bir ilişki belirlenemese de, epidural anestezinin daha az kan kaybı ve daha az kan transfüzyonuna neden olduğu saptanmıştır. Ayrıca venöz tromboemboli görülme sıklığının yaş ve cerrahi süre ile orantılı olarak arttığı belirlenmiştir.

Yaşlı hastalarda anestezi yönteminin total kalça protezi sonrası derin ven trombozuna etkisi

Background: Because hip fractures are common in elderly patients, total hip replacement has been a major advancement in treatment. This procedure, however, is associated with significant postoperative complications such as venous thromboembolism. In this study we retrospectively analyzed the factors affecting the incidence of venous thromboembolism complication which is related with the postoperative morbidity and mortality and its relation with the type of anaesthesia in elderly patients undergoing total hip replacement for traumatic hip fracture. Materials and Methods: We retrospectively reviewed the data of patients aged more than 65 years old, who have undergone total hip replacement after traumatic hip fracture at our institution between 1997 and 2003. The data included patients’ demographic characteristics, intraoperative and postoperative findings, venous thromboembolism incidence and its relation with anesthetic technique. Results: Venous thromboembolism was diagnosed in 10.8% of 291 patients. The incidence of venous thromboembolism was 10.5% after general anaesthesia and 9.2% after epidural anaesthesia (p>0.05). Conclusions: We found no association between the incidence of venous thromboembolism and the type of anaesthesia, although there were some advantages such as less blood lost and fewer blood transfusions with epidural anaesthesia. However, a significant correlation was found between venous thromboembolism and the patient’s age and duration of surgery.

___

  • 1) Kelsey JL, Hoffman S. Risk factors for hip fracture. N Engl J Med 1987; 316: 404-406.
  • 2) Dauphin A, Raymer KE, Stanton EB, et al. Comparison of general anesthesia with and without lumbar epidural for total hip arthroplasty: effects of epidural block on hip arthroplasty. J Clin Anesth 1997; 9: 200-203.
  • 3) Salzman EW, Harris WH. Prevention of venous thromboembolism in orthopaedic patients. J Bone Joint Surg Am 1976; 58A: 903-913.
  • 4) Sharnoff JG, Rosen RL, Sadler AH, et al. Prevention of pulmonary thromboembolism by heparin prophylaxis after surgery for hip fractures. J Bone Joint Surg Am 1976; 58A: 913-918.
  • 5) Urwin SC, Parker MJ, Griffiths R. General versus regional anaesthesia for hip fracture surgery: a meta-analysis of randomized trials. Br J Anaesth 2000; 84: 450-455.
  • 6) Davis FM, Laurenson VG. Spinal anesthesia or general anesthesia for emergency hip surgery in elderly patients. Anaesth Intensive Care 1981; 9: 352-358.
  • 7) McKenzie PJ, Loach AB. Local anaesthesia for orthopaedic surgery. Br J Anaesth. 1986; 58: 779-789.
  • 8) Modig J, Borg T, Karlstrom G, et al. Thromboembolism after total hip replacement: role of epidural and general anesthesia. Anesth Analg 1983; 62: 174-180.
  • 9) Sharrock NE, Ranawat CS, Urquhart B. Factors influencing deep vein thrombosis following total hip arthroplasty under epidural anesthesia. Anesth Analg 1993; 76: 765-771.
  • 10) Sharrock NE, Brien WW, Salvati EA,et al. The effect of intravenous fixed dose heparin during total hip arthroplasty on the incidence of deep venous thrombosis. A randomized double-blind trial in patients operated on with epidural anesthesia and controlled hypotension. J Bone Joint Surg Am 1990; 72A: 1456-1461.
  • 11) Torholm C, Broeng L, Jorgensen PS, et al. Thromboprophylaxis by low-molecular-weight heparin in elective hip surgery. J Bone Joint Surg Br 1991; 73: 434-438.
  • 12) Ogawa S, Gerlach H, Esposito C, et al. Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium. Increased monolayer permeability and induction of procoagulant properties. J Clin Invest 1990; 85: 1090-1098.
  • 13) Hamer JD, Malone PC, Silver IA. The PO2 in venous valve pockets: its possible bearing on thrombogenesis. Br J Surg 1981; 68: 166-170.
  • 14) Goldman L. Cardiac risk in noncardiac surgery: an update. Anesth Analg 1995; 80: 810-820.
  • 15) Hole A, Terjesen T, Breivik H. Epidural versus general anaesthesia for total hip arthroplasty in elderly patients. Acta Anaesthesiol Scand 1980; 24: 279-287.
  • 16) Wolters U, Wolf T, Stutzer H, et al. ASA classification and perioperative variables as predictors of postoperative outcome. Br J Anaesth 1996; 77: 217-222.
  • 17) Handoll HH, Farrar MJ, McBirnie J, et al. Heparin, low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following surgery for hip fractures. Cochrane Database Syst Rev 2002; (4): CD000305.
  • 18) Covert CR, Fox GS. Anaesthesia for hip fracture in elderly. Can J Anaesth 1989; 36: 311-319.
  • 19) O’Hara DA, Duff A, Berlin JA, et al. The effect of anesthetic technique on postoperative outcomes in hip fracture repair. Anesthesiology 2000; 92: 947-957.
  • 20) Yeager MP, Glass DD, Neff RK, et al. Epidural anesthesia and analgesia in high-risk surgical patients. Anesthesiology 1987; 66: 729-736.
  • 21) Williams-Russo P, Sharrock NE, Haas SB, et al. Randomized trial of epidural versus general anesthesia: outcomes after primary total knee replacement. Clin Orthop Relat Res 1996; 331:199-208.
  • 22) Leali A, Fetto J, Moroz A. Prevention of thromboembolic disease after non-cemented hip arthroplasty. A multimodal approach. Acta Orthop Belg 2002; 68: 128-134.
Marmara Medical Journal-Cover
  • ISSN: 1019-1941
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1988
  • Yayıncı: Marmara Üniversitesi
Sayıdaki Diğer Makaleler

Metoclopramide induced acute dystonic reaction: Two case reports

Faruk İNCECİK, YUSUF ÖNLEN, Cahit ÖZER, Kenan ÖZCAN

PAPİLLİT: AĞIR SEPSİSİN NADİR GÖRÜLEN KOMPLİKASYONU

Tümay UMUROĞLU, Feyza İNCİ, Sumru ÖNAL, F. GÖĞÜŞ, Haluk KAZOKOĞLU, Varlık DOĞAN

Bir olgu nedeniyle gaucher hastalığının gözden geçirilmesi

Hasan MIĞIN, Atalay SÜRERDAMAR, Uğur ERSOY, Murat GÜCÜN, Seynur ILGAR, M. Fatih AKDOĞAN, Haluk ŞAVLI

FRANSA DA MASTEKTOMİZE OLAN HASTALARDA ‘SİLİMA DİRECT’ İSİMLİ ADHESİVE PROTEZİN DEĞERLENDİRMESİ

Banu KALPAKCIOĞLU, Matthias FINK, A. TSIOKAS, H. HERMANN

METOKLOPRAMİDE BAĞLI AKUT DİSTONİK REAKSİYON: İKİ OLGU SUNUMU

Faruk İNCECİK, Yusuf ÖNLEN, Cahit ÖZER, Kenan ÖZCAN

Papillitis: A rare complication of severe sepsis

Tümay UMUROĞLU, Feyza İNCİ, Sumru ÖNAL, F. Yılmaz GÖĞÜŞ, Haluk KAZOKOĞLU, Varlık DOĞAN

Doctors’ knowledge level and attitudes concerning avian influenza

Arzu UZUNER, Pemra Ünalan CÖBEK, Hande ALİBAŞ, İrem KILIÇ, Murat SARI, Elif KARAKOÇ, Akbar AKBAROV

Mast hücrelerinin enflamasyondaki rolü: İnsan ve deneysel hayvan modelleri üzerinde yapılan çalışmaların değerlendirilmesi

Feriha ERCAN, Şule ÇETİNEL

RENAL B-MOD ULTRASONOGRAFİ BULGULARININ DİABETİK NEFROPATİ EVRESİ İLE İLİŞKİSİ

Özlem TÜRKSOY, Hüsnü TOKGÖZ, Eda ELVERİCİ, Şule DİLMAN, Enis YÜKSEL

Renal kolik, tanı ve tedavisi

Ahmet Yaser MÜSLÜMANOĞLU, Abdülkadir TEPELR