MENOPOZAL GEÇİŞ DÖNEMİNDE HORMONLAR VE SEKSÜEL FONKSİYONLAR

Amaç: Menopozal geçiş döneminde hormonların (androjen ve östrojenler) kadın seksüalitesine ve psikososyal durumuna etkisi tartışmalıdır. Yöntem: Bu çalışmamızda perimenopozal hastalarda hormonal değişimlerin seksüel fonksiyonlar üzerine değişimini inceledik. Bulgular: DHEAS, FSH, LH, östradiol ve serbest testesteron arasında yalnızca serbest testesteronun anlamlı olarak etki ettiğini gördük (P

-

-
Keywords:

-,

___

  • 1. Sarrel P, Whitehead M. Sex and menopause: defining the issues. Maturitas 1985;7:217-224.
  • 2. Davis SR. Androgen treatment in women. Med J Aust 1999;170:545-549.
  • 3. Zumoff B, Strain GW, Miller LK, et al. twenty four hour mean plasma testesterone concentration declines with age in normal premenopausal women. J Clin Endocrinol Metabol 1995;80:1429-1430.
  • 4. Ravaglia G, Forti P, Maioli F, et al. The relationship of dehydroepiandresterone sulphate (DHEAS) to endocrine-metabolic parameters and functional status in the oldest-old. Results from an Italian study on healthy free-living over ninety-year-olds. J Clin Endocrinol Metabol 1996;81:1173-1178.
  • 5. Dennerstein L, Randolph J, Taffe J, et al. Hormones, mood, sexuality, and the menopausal transition. Fertil and Steril 2002;77:S42-S48.
  • 6. Avis NE, Stellato R, Crawford S, Johannes C, et al. Is there an association between menopause status and sexual functioning? Menopause 2000;7:297-309.
  • 7. Rosen R. Androgens and women’s sexuality: scientific, clinical, and regulatory perspectives. Lecture. Vancouer, BC: International society for the study of Women’s Sexual Health, October 11,2002.
  • 8. Lobo R. Comparative effects of oral esterified estrogens with and without methyltestesterone on endocrine profiles and dimensions of sexual function in postmenopausal women with hypoactive sexual desire. Fertil Steril 2003;79:1341-1352.
  • 9. Dennerstein L, Dudley E, Burger H, et al. Are changes in sexual functioning during midlife due to aging or menopause? Fertil Steril 2001;76:456-460.
  • 10. Dennerstein L, Lehert P. Modelling mid-aged women’s sexual functioning: a prospective, population-based study. J Sex Marital Ther 2004;30:173-183.
  • 11. Nunnally J. Psychometric theory. 2nd ed New York: McGraw Hill, 1978:701.
  • 12. Davis SR, McCloud P, Strauss BJG, et al. Testesterone enhances eustrodiols effects on postemenopausal bone density and sexuality. Maturitas 1995;21:227-236.
  • 13. Sarrel P, Dobay B, Wiita B. Estrogen and estrogenandrogen replacement in postmenopausal women dissatisfied with estrogen only therapy. J Reprod Med 1998;43:847-856.
  • 14. Burger H, Dudley E, Hopper J, et al. Prospectively measured levels of serum FSH, estradiol, and the dimeric inhibins during the menopausal transition in a population based cohort of human. J Clin Endocrinol Metab 1999;84:4025-4030.
  • 15. Gerber JR, Johnson JV, Bunn JY, et al. A longitudinal study of the effects of free testosterone and other psycho social variables on sexual function during the natural traverse of menopause. Fertil Steril 2005;83:643-648.
  • 16. Dennerstein L, Lehert P, Burger H, et al. Mood and the menopausal transition. J Nerv Ment Dis 1999;187:685- 691.
  • 17. Dennerstein L, Burrows GD, Hyman G, et al. Hormon therapy and affect. Maturitas 1979;1:247-259.
  • 18. Dennerstein L, Lehert P, Burger H, et al. Factors affecting sexual functioning of women in the midlife years. Climacteric 1999;2:254-262.
Marmara Medical Journal-Cover
  • ISSN: 1019-1941
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1988
  • Yayıncı: Marmara Üniversitesi